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Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
(Springer Nature, 2018)
To characterize the genetic determinants of resistance to antituberculosis drugs, we performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis clinical isolates from more than 30 countries. A ...
Genome-wide association study for feedlot average daily gain in Nellore cattle (Bos indicus)
(Wiley-Blackwell, 2014-06-01)
The genome-wide association study (GWAS) results are presented for average daily gain (ADG) in Nellore cattle. Phenotype of 720 male Bos indicus animals with information of ADG in feedlots and 354147 single-nucleotide ...
A genome-wide association study of asthma symptoms in Latin American children
(BioMed Central, 2015-12)
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
(Springer Nature, 2016)
We report a genome-wide association scan in over 6,000 Latin Americans for features of scalp hair (shape, colour, greying, balding) and facial hair (beard thickness, monobrow, eyebrow thickness). We found 18 signals of ...
Genome-wide association study and heritability estimate for ectopic ureters in Entlebucher mountain dogs
(2018-12-01)
An ectopic ureter is a congenital anomaly which may lead to urinary incontinence and without a surgical intervention even to end-stage kidney disease. A genetic component contributes to the development of this anomaly in ...
Combined genome-wide association study of 136 quantitative ear morphology traits in multiple populations reveal 8 novel loci
(PLoS, 2023)
Human ear morphology, a complex anatomical structure represented by a multidimensional set of correlated and heritable phenotypes, has a poorly understood genetic architecture. In this study, we quantitatively assessed 136 ...
Marker-assisted selection and genomic selection
(2017-06-10)
Breeding techniques and molecular tools, i.e., biotechnology, have increased crop yield over the last century. Marker-assisted selection and, more recently, genome-wide association studies and genomic selection have been ...
Genome-wide association study of blood pressure extremes identifies variant near umod associated with hypertension
(PUBLIC LIBRAY OF SCIENCE, 2010)
Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans
(Public Library of Science, 2018)
Hair plays an important role in primates and is clearly subject to adaptive selection. While humans have lost most facial hair, eyebrows are a notable exception. Eyebrow thickness is heritable and widely believed to be ...