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Genetics of rheumatoid arthritis: A new boost is needed in Latin American populations
(Elsevier Editora Ltda, 2016)
Malaria Molecular Epidemiology: Lessons from the International Centers of Excellence for Malaria Research Network
(American Society of Tropical Medicine and Hygiene, 2015)
Molecular epidemiology leverages genetic information to study the risk factors that affect the frequency and distribution of malaria cases. This article describes molecular epidemiologic investigations currently being ...
Development and internal validation of a multifactorial risk prediction model for gallbladder cancer in a high-incidence country
(Wiley, 2023)
Since 2006, Chile has been implementing a gallbladder cancer (GBC) prevention program based on prophylactic cholecystectomy for gallstone patients aged 35 to 49 years. The effectiveness of this prevention program has not ...
Linking genetic and environmental factors in amphibian disease risk
(Wiley-Blackwell, 2015-07-01)
A central question in evolutionary biology is how interactions between organisms and the environment shape genetic differentiation. The pathogen Batrachochytrium dendrobatidis (Bd) has caused variable population declines ...
Factor V Arg306 → Thr (factor V Cambridge) and factor V Arg306 → Gly mutations in venous thrombotic disease
(Blackwell Science, 1998-01-01)
We investigated the prevalence of two reported mutations of the factor V gene (factor V Arg306 → Thr, or factor V Cambridge, and factor V Arg306 → Gly) in 104 relatively young patients with verified venous thrombosis and ...
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
(Nature Research, 2023)
The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but the underlying biology is unknown. Using multi-ancestry ...
Socioeconomic and nutritional factors account for the association of gastric cancer with amerindian ancestry in a latin american admixed population
(Public Library of Science, 2012)
Gastric cancer is one of the most lethal types of cancer and its incidence varies worldwide, with the Andean region of South America showing high incidence rates. We evaluated the genetic structure of the population from ...