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Mostrando ítems 1-10 de 2023
Sex differences in X-linked gene expression in embryonic hypothalamic neurons
(Sociedad Argentina de Investigación en Neurociencias, 2017)
Although sex hormones are usually considered the main architects of sexual dimorphisms, recent studies have demonstrated that sex chromosomes can also induce sex differences in somatic gene expression in the absence of ...
Role of X-linked genes on sex differences in neurogenin 3 expression in developing hypothalamic neurons
(2016)
Our previous findings indicate that sex chromosome complement regulates the generation of sex differences in mouse hypothalamic neuronal development. Higher expression of neurogenin 3 (Ngn3) in XX neurons mediates sex ...
Sex differences in gene expression of X-linked histone demethylase Kdm6a in embryonic hypothalamic neurons
(2018)
Kdm6a and Kdm5c are histone demethylases that play an important role as epigenetic regulators of gene transcription by removing the di- and tri-methylation of Lys27 or Lys4 on histone H3 (H3K27me2/me3 - H3K4me2/me3). Both ...
Similar interstitial deletions of the KAL-1 gene in two Brazilian families with X-linked Kallmann Syndrome
(Sociedade Brasileira de Genética, 2004)
Mutations of Bruton's tyrosine kinase gene in Brazilian patients with X-linked agammaglobulinemia
(Associação Brasileira de Divulgação Científica, 2010)
Mutations in Bruton's tyrosine kinase (BTK) gene are responsible for X-linked agammaglobulinemia (XLA), which is characterized by recurrent bacterial infections, profound hypogammaglobulinemia, and decreased numbers of ...
X-linked intellectual disability related genes disrupted by balanced X-autosome translocations
(2015-12-01)
Detailed molecular characterization of chromosomal rearrangements involving X-chromosome has been a key strategy in identifying X-linked intellectual disability-causing genes. We fine-mapped the breakpoints in four women ...
Report of a new mutation in CYBB gene in two patients with X linked chronic granulomatous disease
(Soc Medica SantiagoSantiago 9Chile, 2006)
Characterization of allele-specific expression of the X-linked gene MAO-A in trophectoderm cells of bovine embryos produced by somatic cell nuclear transfer
(Funpec-editora, 2015-01-01)
Somatic cell nuclear transfer (SCNT) may affect epigenetic mechanisms and alter the expression of genes related to embryo development and X chromosome inactivation (XCI). We characterized allele-specific expression of the ...