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Gastric Damage and Cancer-Associated Biomarkers in Helicobacter pylori-Infected Children
(Frontiers Media, 2020)
Helicobacter pylori (H. pylori) is well-known to be involved in gastric carcinogenesis, associated with deregulation of cell proliferation and epigenetic changes in cancer-related genes. H. pylori infection is largely ...
Noncoding Genomics In Gastric Cancer And The Gastric Precancerous Cascade: Pathogenesis And Biomarkers
(2015)
Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related death, whose patterns vary among geographical regions and ethnicities. It is a multifactorial disease, and its development depends ...
Role of Reprimo-like as a a tumor suppressor and candidate biomarker in gastric cancer
(2020)
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Herein, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. ...
The reprimo-like gene is an epigenetic-mediated tumor suppressor and a candidate biomarker for the non-invasive detection of gastric cancer
(MDPI, 2020)
Reprimo-like (RPRML) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of RPRML and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML ...
Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer
(Baishideng Publishing Group Inc, 2016)
Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic miRNAs and downregulated ...
Current advances in targeted therapies for metastatic gastric cancer: improving patient care
(Future medicine ltd, 2016)
In this article, we review the literature on the current advances in targeted therapies for metastatic gastric cancer aimed at improving patient care. We conclude that the key to guiding targeted therapy is individual ...
The low-abundance transcriptome reveals novel biomarkers, specific intracellular pathways and targetable genes associated with advanced gastric cancer
(Wiley, 2014-02)
Studies on the low-abundance transcriptome are of paramount importance for identifying the intimate mechanisms of tumor progression that can lead to novel therapies. The aim of the present study was to identify novel markers ...
Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer
(Bentham, 2015)
Organic and inorganic nanoparticles show great potential for cancer diagnosis and treatment. Because gastric cancer (GC) represents the second most deadly type of neoplasia worldwide, continued research efforts by scientists ...