Buscar
Mostrando ítems 1-10 de 25
Peptides and peptide-derived molecules targeting the intracellular domains of Cx43: gap junctions versus hemichannels
(Elsevier, 2013)
About a decade ago, the molecular determinants controlling the opening and closing of Cx43 gap junction channels have been identified. Advanced biophysical approaches revealed a critical role for structural rearrangements ...
Peptides and peptide-derived molecules targeting the intracellular domains of Cx43: gap junctions versus hemichannels
(Elsevier, 2013)
About a decade ago, the molecular determinants controlling the opening and closing of Cx43 gap junction channels have been identified. Advanced biophysical approaches revealed a critical role for structural rearrangements ...
Regulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channels
(2012)
The synchronization of numerous cellular events requires complex electric and metabolic cell-cell interactions. Connexins are a family of membrane proteins that constitute the molecular basis of two kinds of channels: gap ...
Carbon monoxide: A new player in the redox regulation of connexin hemichannels
(International Union of Biochemistry and Molecular Biology, 2015)
Carbon monoxide (CO) is a gaseous transmitter that is known to be involved in several physiological processes, but surprisingly it is also becoming a promising molecule to treat several pathologies including stroke and ...
Carbon monoxide: A new player in the redox regulation of connexin hemichannels
(International Union of Biochemistry and Molecular Biology, 2015)
Carbon monoxide (CO) is a gaseous transmitter that is known to be involved in several physiological processes, but surprisingly it is also becoming a promising molecule to treat several pathologies including stroke and ...
Differential effects of trimethylamine and quinine on seizures induced by 4-aminopyridine administration in the entorhinal cortex of vigilant rats
(2010)
In vivo and in vitro evidence from animals suggesting that gap junctions (GJs) play a role in the spreading of epileptiform activity. We have examined the influence of the gap junction opener trimethylamine (TMA) and the ...
Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+](i) responses
(AMER SOC CELL BIOLOGY, 2008)
Cell surface hemichannels (HCs) composed of different connexin (Cx) types are present in diverse cells and their possible role on FGF-1-induced cellular responses remains unknown. Here, we show that FGF-1 transiently (4-14 ...
Diffuse reflectance spectroscopy and Optical polarization imaging of in-vivo biological tissue
(2010)
In vivo and in vitro evidence from animals suggesting that gap junctions (GJs) play a role in the spreading of epileptiform activity. We have examined the influence of the gap junction opener trimethylamine (TMA) and the ...