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Participation of the GABAergic system on the glutamate release of frontal cortex synaptosomes from Wistar rats with experimental autoimmune encephalomyelitis
(Pergamon-Elsevier Science Ltd, 2011-08)
We previously found that the glutamate release was decreased in synaptosomes from rat cerebral cortex during the development of experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis. Various ...
Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012-01)
Tonic immobility (TI) is an innate defensive behavior that can be elicited by physical restriction and postural inversion and is characterized by a profound and temporary state of akinesis. Our previous studies demonstrated ...
Role of cholinergic, opioidergic and GABAergic neurotransmission of the dorsal hippocampus in the modulation of nociception in guinea pigs
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Aims: Several physiological, pharmacological and behavioral lines of evidence suggest that the hippocampal formation is involved in nociception. The hippocampus is also believed to play an important role in the affective ...
The involvement of the GABAergic system in the formation and expression of the extinction memory in the crab Neohelice granulata
(Wiley, 2013-11)
There is growing interest in the neurobiological mechanisms involved in the extinction of aversive memory. This cognitive process usually occurs after repeated or prolonged presentation of a conditioned stimulus that was ...
Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity
(Frontiers Media Sa, 2019-09-20)
Dysregulation of the corticotropin-releasing hormone (CRH) system has been implicated in stress-related psychopathologies such as depression and anxiety. Although most studies have linked CRH/CRH receptor 1 signaling to ...
Lipophilicity of some GABAergic phenols and related compounds determined by HPLC and partition coefficients in different systems
(Elsevier Science, 2009-04-05)
Some phenolic compounds, like propofol and thymol, have been shown to act on the GABAA receptor. Taking into account the hydrophobicity of these compounds, their interaction with the membrane surrounding the receptor and ...
A motogenic gabaergic system of mononuclear phagocytes facilitates dissemination of coccidian parasites
(2020-10)
Gamma-aminobutyric acid (GABA) serves diverse biological functions in prokaryotes and eukaryotes, including neurotransmission in vertebrates. Yet, the role of GABA in the immune system has remained elusive. Here, a ...
The GABAergic system contributes to the anxiolytic-like effect of essential oil from Cymbopogon citratus (lemongrass)
(ELSEVIER IRELAND LTD, 2011)
Ethnopharmacological relevance: The essential oil (EO) from Cymbopogon citratus (DC) Stapf is reported to have a wide range of biological activities and is widely used in traditional medicine as an infusion or decoction. ...
The GABAergic system contributes to the anxiolytic-like effect of essential oil from Cymbopogon citratus (lemongrass)
(Elsevier B.V., 2011-09-01)
Ethnopharmacological relevance: The essential oil (EO) from Cymbopogon citratus (DC) Stapf is reported to have a wide range of biological activities and is widely used in traditional medicine as an infusion or decoction. ...