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GSK-3 beta/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy
(2016)
Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear factor of activated T-cells (NFAT) is associated with the promotion ...
Platelet GSK3B activity in patients with late-life depression: Marker of depressive episode severity and cognitive impairment?
(INFORMA HEALTHCARE, 2011)
Objective. Increased GSK3B activity has been reported as a state marker of major affective episodes in patients with depression and bipolar disorder. No study so far has addressed GSK3B activity in late-life depression. ...
Increased platelet GSK3B activity in patients with mild cognitive impairment and Alzheimer`s disease
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
The disruption of glycogen synthase kinase 3-beta (GSK3B) homeostasis has implications in the pathophysiology of neuropsychiatric disorders, namely Alzheimer`s disease (AD). GSK3B activity is increased within the AD brain, ...
Gsk-3 Inhibitors mimic the cardioprotection mediated by ischemic pre- and postconditioning in hypertensive rats
(Hindawi Publishing Corporation, 2013-09)
The aim of this study was to examine the effects of GSK-3 inhibitors compared with PRE and POS in spontaneously hypertensive rats (SHR). Isolated hearts were submitted to the following protocols: IC: 45 min global ischemia ...
Gsk-3 β inhibitors mimic the cardioprotection mediated by ischemic pre- and postconditioning in hypertensive rats
(Hindawi Publishing Corporation, 2013-10)
The aim of this study was to examine the effects of GSK-3β inhibitors compared with PRE and POS in spontaneously hypertensive rats (SHR). Isolated hearts were submitted to the following protocols: IC: 45 min global ischemia ...
Insights into the Interactions between Maleimide Derivates and GSK3 beta Combining Molecular Docking and QSAR
(PUBLIC LIBRARY SCIENCE, 2014)