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The value of dog for knowledge of human Duchenne muscular dystrophy: New findings in pathogenesis and therapeutic advances
(2015-04-01)
Duchenne muscular dystrophy (DMD) is the most devastating form of inherited muscular dystrophy in men. The loss of dystrophin causes progressive weakness and degeneration of skeletal and cardiac muscle leading to the ...
Utrophin, MHC and M1/M2 macrophages in GRMD dogsUtrofina, MHC e macrófagos M1 e M2 em cães DMGR
(2020-01-01)
Muscular dystrophies are hereditary diseases that lead to progressive degeneration of the skeletal musculature. Golden Retriever dogs are used as animal models because they show a hereditary muscle disease similar to ...
Estudo morfofuncional dos rins de cães da raça Golden Retriever afetados pela distrofia muscular (GRMD)
(REVISTA PESQUISA VETERINARIA BRASILEIRARIO DE JANEIRO, 2012)
A Distrofia Muscular de Duchenne (DMD) é uma miopatia severa de caráter recessivo ligada ao cromossomo X e o modelo animal de estudo mais relevante é o Golden Retriever Muscular Dystrophy (GRMD). Além das severas alterações ...
Predictive markers of clinical outcome in the GRMD dog model of Duchenne muscular dystrophy
(The Company of Biologists Ltd, 2015)
Immunophenotyping lymphocyte and acute phase proteins in canine x-linked muscular dystrophy
(2018-07-01)
Duchenne Muscular Dystrophy (DMD) is the most common X-linked muscular disease affecting humans. The Golden Retriever Muscular Dystrophy model (GRMD) is consider the most suitable for several studies. This assay aims to ...
Importância dos mastócitos na patogênese da distrofia muscular de Duchenne em cães Golden Retriever
(Universidade Estadual Paulista (Unesp), 2015-09-30)
Golden Retriever Muscular Dystrophy (GRMD) is the best natural model of Duchenne muscular dystrophy (DMD) with genotypic and phenotypic manifestations similar the human disease. As in to DMD patients, the progressive ...
Profiles Of Steroid Hormones In Canine X-linked Muscular Dystrophy Via Stable Isotope Dilution Lc-ms/ms
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2015)
Predictive markers of clinical outcome in the GRMD dog model of Duchenne muscular dystrophy
(The Company of Biologists Ltd, 2014)