Buscar
Mostrando ítems 1-10 de 16
Mass spectrometry glycophenotype characterization of ALG2-CDG in Argentinean patients with a new genetic variant in homozygosis
(Springer, 2021-04)
Human ALG2 encodes an α 1,3mannosyltransferase that catalyzes the first steps in the synthesis of N-glycans in the endoplasmic reticulum. Variants in ALG2cause a congenital disorder of glycosylation (CDG) known as ALG2-CDG. ...
Aberrant O-glycosylation modulates aggressiveness in neuroblastoma
(Impact Journals, 2018-09)
Neuroblastoma (NB) is the most common pediatric malignancy diagnosed before the first birthday in which MYCN oncogene amplification is associated with poor prognosis. Although aberrant glycosylation is an important actor ...
Impacto do microambiente hipóxico e/ou privado de soro sobre o glicofenótipo de modelos in vitro do câncer de mama
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Inovacao Terapeutica, 2019)
Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3
(Biolife Sas, 2009)
A breakdown in intestinal homeostasis results in inflammatory bowel diseases including coeliac disease and allergy. Galectins, evolutionarily conserved beta-galactoside-binding proteins, can modulate immune-epithelial cell ...
Identificação quimiluminescente do perfil de carboidratos e antígenos teciduais em modelo experimental de esquistossomose mansônicaAnálise do perfil de antígenos teciduais em esquistossomose mansônica mediante a uso de técnicas quimiluminescentes
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Biologicas, 2019)
Galectin-1 Prevents Infection and Damage Induced by Trypanosoma cruzi on Cardiac Cells
(Public Library of Science, 2015-10-09)
Chronic Chagas cardiomyopathy caused by Trypanosoma cruzi is the result of a pathologic process starting during the acute phase of parasite infection. Among different factors, the specific recognition of glycan structures ...
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)
(Elsevier Ireland, 2021-10-10)
Tn is a tumor-associated carbohydrate antigen that constitutes both a diagnostic tool and an immunotherapeutic target. It originates from interruption of the mucin O-glycosylation pathway through defects involving, at least ...
Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF
(Impact Journals, 2017-04)
Neovascular retinopathies are leading causes of irreversible blindness. Although vascular endothelial growth factor (VEGF) inhibitors have been established as the mainstay of current treatment, clinical management of these ...
Análise da expressão de glicosiltransferases em tumores cutâneos não melanomas
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Inovacao Terapeutica, 2017)