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GibbsCluster: unsupervised clustering and alignment of peptide sequences
(Oxford University Press, 2017-04)
Receptor interactions with short linear peptide fragments (ligands) are at the base of many biological signaling processes. Conserved and information-rich amino acid patterns, commonly called sequence motifs, shape and ...
Computational Tools for the Identification and Interpretation of Sequence Motifs in Immunopeptidomes
(Wiley VCH Verlag, 2018-06)
Recent advances in proteomics and mass‐spectrometry have widely expanded the detectable peptide repertoire presented by major histocompatibility complex (MHC) molecules on the cell surface, collectively known as the ...
Improved Prediction of Bovine Leucocyte Antigens (BoLA) Presented Ligands by Use of Mass-Spectrometry-Determined Ligand and in Vitro Binding Data
(American Chemical Society, 2018-01)
Peptide binding to MHC class I molecules is the single most selective step in antigen presentation and the strongest single correlate to peptide cellular immunogenicity. The cost of experimentally characterizing the rules ...