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Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with cushing s disease
(Sociedade Brasileira de Endocrinologia e Metabologia, 2007-10-01)
GH responses to ghrelin, GHRP-6, and GHRH in Cushing s disease (CD) are markedly blunted. There is no data about the effect of reduction of cortisol levels with steroidogenesis inhibitors, like ketoconazole, on GH secretion ...
Absence of GH-Releasing Hormone (GHRH) Mutations in Selected Patients with Isolated GH Deficiency
(ENDOCRINE SOC, 2011)
Context: Although numerous reports of mutations in GH1 and GHRHR (GHRH receptor) causing isolated GH deficiency (IGHD) have been published, mutations in GHRH itself have not been hitherto reported but are obvious candidates ...
Neurotransmitter modulation of the GHRH-GH axis
(Karger, 2010-11)
The role of dopaminergic receptors in the control of GH release remains controversial. The dopamine receptor 2 (D2R) knockout mouse represents a useful model to study the participation of the D2R on growth and GHRH-GH ...
El uso del factor liberador de hormona de crecimiento (GRF) como prueba de reserva hipofisiaria para hormona de crecimiento (hGH) (*)
(Sociedad Chilena de Pediatría, 1986)
Hormônio do crescimento ou somatotrófico: novas perspectivas na deficiência isolada de GH a partir da descrição da mutação no gene do receptor do GHRH nos indivíduos da cidade de Itabaianinha, BrasilGrowth or somatotrophic hormone: new perspectives in isolated GH deficiency after description of the mutation in the GHRH receptor gene in individuals of Itabaianinha county, Brazil
(Sociedade Brasileira de Endocrinologia e Metabologia, 2016)
Função muscular em indivíduos com deficiência isolada do GH devido à mutação no gene do receptor do GHRHMuscle function in individuals with Isolated Growth Hormone Deficiency by genetic mutation GHRH receptor gene
(Pós-Graduação em Ciências Aplicadas à SaúdeUFS, 2020)
Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH
(Bioscientifica Ltd, 2009-11-01)
Objective: in Cushing's disease (CD), GH responsiveness to several stimuli, including ghrelin, GHRP-6, and GHRH. is blunted. Recovery of GH secretion after remission of hypercortisolism after transsphenoidal surgery. ...
Growth hormone responses to GH-releasing peptide (GHRP-6) in hypothyroidism
(Wiley-Blackwell, 1997-03-01)
OBJECTIVE Both spontaneous and stimulated GH secretion are reduced in patients with hypothyroidism. the mechanisms involved in these alterations are not yet fully understood, GHRP-6 is a synthetic hexapeptide that releases ...
The effects of β1-adrenergic blockade on the growth response to growth hormone (GH)-releasing hormone therapy in GH-deficient children
(1995)
Acute suppression of SRIH secretion with a β-adrenergic antagonist can increase the GH response to GHRH.To determine whether chronic β-blockade could enhance the growth-promoting effects of GHRH therapy, we conducted a ...