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Genetic Mutations in the GH/IGF Axis
(Medical Media, 2018-09)
The GH/IGF axis plays an important role in the control of pre and postnatal growth. At least 48 monogenic defects have been described affecting the production, secretion, and action of GH and IGFs. Molecular defects of the ...
Arginine induces GH gene expression by activating NOS/NO signaling in rat isolated hemi-pituitaries
(Associação Brasileira de Divulgação Científica, 2012)
The amino acid arginine (Arg) is a recognized secretagogue of growth hormone (GH), and has been shown to induce GH gene expression. Arg is the natural precursor of nitric oxide (NO), which is known to mediate many of the ...
Polimorfismos no gene do hormônio do crescimento associado a características de crescimento de Tilápia do Nilo
(Universidade Estadual de MaringáBrasilDepartamento de ZootecniaPrograma de Pós-Graduação em ZootecniaUEMMaringá, PRCentro de Ciências Agrárias, 2018)
Genetic disorders of GH action pathway
(Churchill Livingstone, 2018-02)
While insensitivity to GH (GHI) is characterized by low IGF-I levels, normal or elevated GH levels, and lack of IGF-I response to GH treatment, IGF-I resistance is characterized by elevated IGF-I levels with normal/high ...
Identification and characterization of polymorphisms within the 5' flanking region, first exon and part of first intron of bovine GH gene
(Blackwell Publishing, 2006-06-01)
The aim of the present study was to identify and characterize polymorphisms within the 5' flanking region, first exon and part of first intron of the bovine growth hormone gene among different beef cattle breeds: Nelore ...
Identification and characterization of polymorphisms within the 5' flanking region, first exon and part of first intron of bovine GH gene
(Blackwell Publishing, 2006-06-01)
The aim of the present study was to identify and characterize polymorphisms within the 5' flanking region, first exon and part of first intron of the bovine growth hormone gene among different beef cattle breeds: Nelore ...
Multiple mechanisms of growth hormone-regulated gene transcription
(Elsevier, 2007)
Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and ...
Consequences of lifetime isolated growth hormone (GH) deficiency and effects of short-term GH treatment on bone in adults with a mutation in the GHRH-receptor gene
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Growth hormone (GH) influences bone mass maintenance. However, the consequences of lifetime isolated GH deficiency (IGHD) on bone are not well established. We assessed the bone status and the effect of 6 months of GH ...
A comparative expression analysis of gene transcripts in brain tissue of non-transgenic and GH-transgenic zebrafish (Danio rerio) using a DDRT-PCR approach
(Academia Brasileira de Ciências, 2012-06-01)
A presença de níveis mais elevados do hormônio de crescimento (GH) em animais transgênicos poderia levar a várias alterações fisiológicas. Uma linhagem transgênica de paulistinha (Danio rerio) para o GH foi comparada com ...
A comparative expression analysis of gene transcripts in brain tissue of non-transgenic and GH-transgenic zebrafish (Danio rerio) using a DDRT-PCR approach
(Academia Brasileira de Ciências, 2012-06-01)
A presença de níveis mais elevados do hormônio de crescimento (GH) em animais transgênicos poderia levar a várias alterações fisiológicas. Uma linhagem transgênica de paulistinha (Danio rerio) para o GH foi comparada com ...