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Chemical event chain model of coupled genetic oscillators
(American Physical Society, 2018-03)
We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states ...
Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations
(Instituto de Física de Líquidos y Sistemas Biológicos, 2014-12)
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence of cooperative binding, and consider ...
Precision of genetic oscillators and clocks
(American Physical Society, 2007-12)
We develop a stochastic description of feedback oscillators in which functional molecules are produced by an assembly line consisting of many identical steps. The initiation rate of this assembly is regulated by its products ...
Role of transcriptional bursts in cellular oscillations
(Academic Press Ltd - Elsevier Science Ltd, 2017-08-24)
Genetic oscillators are present in the cells of many organisms and control several biological processes. The common feature of such oscillators is the presence of a protein which represses the transcription of its own gene. ...
Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock
(eLife Sciences Publications, 2016-02)
In vertebrate development, the sequential and rhythmic segmentation of the body axis is regulated by a "segmentation clock". This clock is comprised of a population of coordinated oscillating cells that together produce ...
Analysis of the Influence of IPFC-POD and PSS controllers coordinated tuning by an Adaptive Genetic Algorithm with Hyper-mutation
(Ieee, 2018-01-01)
Small-magnitude disturbances happen to produce electro-mechanical oscillations which should be damped as quickly as possible to ensure reliability and stability of electrical power system (EPS). Flexible AC transmission ...
Analysis of the Influence of IPFC-POD and PSS controllers coordinated tuning by an Adaptive Genetic Algorithm with Hyper-mutation
(2019-01-07)
Small-magnitude disturbances happen to produce electro-mechanical oscillations which should be damped as quickly as possible to ensure reliability and stability of electrical power system (EPS). Flexible AC transmission ...
Sintonia automática e coordenada de controladores de sistema de potência utilizando algoritmo genético multiobjetivo
(Universidade Tecnológica Federal do ParanáCornelio ProcopioBrasilEngenharia ElétricaUTFPR, 2018-06-07)
The Power System is constantly subjected to disturbances, which is often a result of the unbalance between generation and consumption. These disturbances generate electromechanical oscillations and they can cause the ...
Coordinated tuning of PSS and TCSC-POD controller using an Elite Genetic Algorithm
(2017-03-08)
In this article, an Elite Genetic Algorithm is applied for tuning the parameters of supplementary damping controllers. The strategy of the applied method is to ensure the permanence of elite solutions in the process without ...