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Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activity
(American Physiological Society, 2018-06)
Cellular life requires the activation of the ADP-ribosylation factors (ARFs) by Golgi brefeldin A-resistant factor 1 (GBF1), a guanine nucleotide exchange factor (GEF) with a highly conserved catalytic Sec7 domain (Sec7d). ...
Dengue Virus Uses a Non-Canonical Function of the Host GBF1-Arf-COPI System for Capsid Protein Accumulation on Lipid Droplets
(Wiley, 2015-06)
Dengue viruses cause the most important human viral disease transmittedby mosquitoes. In recent years, a great deal has been learnedabout molecular details of dengue virus genome replication; however,little is known about ...
Characterization of alternatively spliced and truncated forms of the arf guanine nucleotide exchange factor gbf1 defines regions important for activity
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2003)
Gbf1, a cis-golgi and vtcs-localized arf-gef, is implicated in er-to-golgi protein traffic
(CAMBRIDGE UNIVERSITY PRESS, 2006)
Rab1b Interacts with GBF1 and Modulates both ARF1 Dynamics and COPI Association
(American Society for Cell Biology, 2007-07)
Assembly of the cytosolic coat protein I (COPI) complex at the ER-Golgi interface is directed by the ADP ribosylation factor1 (Arf1) and its guanine nucleotide exchange factor (GBF1). Rab1b GTPase modulates COPI recruitment, ...
Potencial farmacológico da macroalga Gracilaria birdiae obtida de diferentes fontes
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Bioquimica e Fisiologia, 2018)
Non-conventional axonal organelles control TRPM8 ion channel trafficking and peripheral cold sensing
(Cell Press, 2020)
TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery ...