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Alfataliglicerase para doença de gaucher: experiência do centro de referência do rio grande do sul
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Bone Diseases as the only clinical manifestation of gaucher disease type
(Sociedad Latinoamericana de Errores Innatos del Metabolismo y Pesquisa Neonatal, 2013)
Gaucher disease (GD) is a lysosomal disease, due to the deficiency of Iˆ2-glucosidase, characterized by invol vement of hematopoietic organs such as the spleen, liver, bone marrow, lung, and bone. Bone is the second most ...
Gaucher disease: a case studyEnfermedad de Gaucher: estudio de caso
(Facultad de Medicina, 2017)
Induction of osteoclastogenesis in an in vitro model of Gaucher disease is mediated by T cells via TNF-α
(Elsevier Science, 2012-11)
Gaucher disease is a lysosomal storage disorder caused by deficiency of glucocerebrosidase enzymatic activity leading to accumulation of its substrate glucocerebrosidase mainly in macrophages. Skeletal disorder of Gaucher ...
Estudo clínico retrospectivo da alfataliglicerase no Hemorio
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease
(Public Library of Science, 2019-05-31)
Gaucher and Fabry diseases are the most prevalent sphingolipidoses. Chronic inflammation is activated in those disorders, which could play a role in pathogenesis. Significant degrees of amelioration occur in patients upon ...
Revised recommendations for the management of Gaucher disease in children
(Springer, 2013-04-01)
Gaucher disease is an inherited pan-ethnic disorder that commonly begins in childhood and is caused by deficient activity of the lysosomal enzyme glucocerebrosidase. Two major phenotypes are recognized: non-neuropathic ...