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GABAB receptors in neuroendocrine regulation
(Springer, 2008-09)
Gamma-amino butyric acid (GABA), in addition to being a metabolic intermediate and the main inhibitory neurotransmitter in the synaptic cleft, is postulated as a neurohormone, a paracrine signaling molecule, and a trophic ...
Ontogenic expression of anterior pituitary GABAB receptor subunits
(Pergamon-Elsevier Science Ltd., 2001)
gamma-Aminobutyric acid (GABA) is involved in the neuroendocrine control of hypophyseal secretion, acting both in the central nervous system and directly at the pituitary. We have characterized the properties of anterior ...
Estudio de la participación de los receptores GABAB en las propiedades adictivas de la nicotina
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2015)
Involvement of GABAB receptors in biochemical alterations induced by anxiety-related responses to nicotine in mice: Genetic and pharmacological approaches
(Elsevier, 2014-01)
Previous studies from our laboratory showed that anxiety-related responses induced by nicotine (NIC), measured by the elevated plus maze, were abolished by 2-OH-saclofen (GABAB receptor antagonist) (1 mg/kg; ip) or the ...
Acute behavioural responses to nicotine and nicotine withdrawal syndrome are modified in GABAB1 knockout mice
(Pergamon-Elsevier Science Ltd, 2012-10)
Nicotine is the main active component of tobacco, and has both acute and chronic pharmacological effects that can contribute to its abuse potential in humans. The aim of the present study was to evaluate a possible role ...
Sex Differences in insulin resistance in GABAB1 knock out mice
(Elsevier, 2012-11-20)
We have previously demonstrated that the absence of functional GABA B receptors (GABABRs) disturbs glucose homeostasis in GABAB1KO mice. The aim of this work was to extend our studies of these alterations in GABAB1KO mice ...
Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal
(Elsevier, 2015-03)
The nicotine (NIC) withdrawal syndrome is considered to be a major cause of the high relapse rate among individuals undergoing smoking cessation. The aim of the present study was to evaluate a possible role of GABAB receptors ...
Marlin-1 is expressed in testis and associates to the cytoskeleton and GABAB receptors
(2008)
Marlin-1 is a GABAB receptor and Jak tyrosine kinase-binding protein that also associates with RNA and microtubules. In humans and rodents, expression of Marlin-1 is predominantly restricted to the brain, but expression ...
Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors
(American Physiological Society, 2013-03-26)
Adult mice lacking functional GABAB receptors (GABAB1KO) have glucose metabolism alterations. Since GABAB receptors (GABABRs) are expressed in progenitor cells, we evaluated islet development in GABAB1KO mice. Postnatal ...