Buscar
Mostrando ítems 1-10 de 1819
Regulación del receptor GABA A inducida por su activación en corteza cerebral de rataActivity-dependent regulation of GABA A receptor in rat cerebral cortex
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2013)
RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity
(Royal Society Of Chemistry, 2013-04)
We have devised a new caged GABA based on ruthenium bipyridyl coordination chemistry. This photo-trigger delivers GABA upon irradiation with wavelengths up to 532 nm undergoing heterolytic photo-cleavage, in a clean and ...
GABAergic mediation of stress-induced secretion of corticosterone and oxytocin, but not prolactin, by the hypothalamic paraventricular nucleus
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The hypothalamus-pituitary-adrenal axis (HPA) participates in mediating the response to stressful stimuli. Within the HPA, neurons in the medial parvocellular region of paraventricular nucleus (PVN) of the hypothalamus ...
An intrinsic GABAergic system in human lymphocytes
(Pergamon-Elsevier Science Ltd, 2011-03)
γ-Amino butyric acid (GABA) is an ubiquitous neurotransmitter in the central nervous system and it is also present in non-neuronal cells. In this study we investigated the presence of neuronal components of the GABAergic ...
GABA-induced uncoupling of GABA/benzodiazepine site interactions is mediated by increased GABAA receptor internalization and associated with a change in subunit composition
(Elsevier, 2014-01)
Persistent activation of GABAA receptors triggers compensatory changes in receptor function that are relevant to physiological, pathological and pharmacological conditions. Chronic treatment of cultured neurons with GABA ...
Assessment of in vitro pharmacological effect of Neotropical Piperaceae in GABAergic bioassays in relation to plants traditionally used for folk illness by the Yanesha (Peru)
(Elsevier, 2014)
ETHNOPHARMACOLOGICAL RELEVANCE: A previous pilot ethnobotanical and ethnopharmacological study with the Q'echi Maya identified the family Piperaceae, as an important taxonomic group traditionally used for the treatment of ...
Analysis of macroscopic ionic currents mediated by GABA ρ1 receptors during lanthanide modulation predicts novel states controlling channel gating
(Wiley Blackwell Publishing, Inc, 2005-12)
1 Lanthanide-induced modulation of GABA(C) receptors expressed in Xenopus oocytes was studied. 2 We obtained two-electrode voltage-clamp recordings of ionic currents mediated by recombinant homomeric GABA ρ1 receptors and ...
GABA released from cultured cortical neurons influences the modulation of t-[35S]butylbicyclophosphorothionate binding at the GABAA receptor: Effects of thymol
(Elsevier Science, 2008-12)
Thymol is a monoterpene that specifically interacts with synaptic neural functions in neuronal GABA-operated Cl- channels. Here we explore the effects of thymol, and propofol as positive control, on t-[35S]butylbicycloph ...
Expression and function of non-neuronal GABA transporters in human lymphocytes
(Asian Network for Scientific Information, 2017-01-15)
Background: Neurotransmitters not only play a key role in neuronal communication but also coordinate cell functions in non-neuronal cells, such as immune cells. Previous research reported a complete GABAergic system in ...