Now showing items 1-10 of 763
Regulación del receptor GABA A inducida por su activación en corteza cerebral de rataActivity-dependent regulation of GABA A receptor in rat cerebral cortex
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2013)
RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity
(Royal Society Of Chemistry, 2013-04)
We have devised a new caged GABA based on ruthenium bipyridyl coordination chemistry. This photo-trigger delivers GABA upon irradiation with wavelengths up to 532 nm undergoing heterolytic photo-cleavage, in a clean and ...
GABAergic mediation of stress-induced secretion of corticosterone and oxytocin, but not prolactin, by the hypothalamic paraventricular nucleus
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The hypothalamus-pituitary-adrenal axis (HPA) participates in mediating the response to stressful stimuli. Within the HPA, neurons in the medial parvocellular region of paraventricular nucleus (PVN) of the hypothalamus ...
GABA-induced uncoupling of GABA/benzodiazepine site interactions is mediated by increased GABAA receptor internalization and associated with a change in subunit composition
Persistent activation of GABAA receptors triggers compensatory changes in receptor function that are relevant to physiological, pathological and pharmacological conditions. Chronic treatment of cultured neurons with GABA ...
Expression and function of non-neuronal GABA transporters in human lymphocytes
(Asian Network for Scientific Information, 2017-01-15)
Background: Neurotransmitters not only play a key role in neuronal communication but also coordinate cell functions in non-neuronal cells, such as immune cells. Previous research reported a complete GABAergic system in ...
GABA released from cultured cortical neurons influences the modulation of t-[35S]butylbicyclophosphorothionate binding at the GABAA receptor: Effects of thymol
(Elsevier Science, 2008-12)
Thymol is a monoterpene that specifically interacts with synaptic neural functions in neuronal GABA-operated Cl- channels. Here we explore the effects of thymol, and propofol as positive control, on t-[35S]butylbicycloph ...
Marlin-1 and conventional kinesin link GABA(B) receptors to the cytoskeleton and regulate receptor transport
The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABA(B) receptors (GABA(B)Rs) to the cytoskeleton have not been described. We recently ...
Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors. GABA and GABA receptors are, however, also present in several ...
Age related changes of the GABA-B receptor in the lumbar spinal cord of male rats and penile erection
(Elsevier Inc, 2006-02)
Dorsal horn neurons of lumbosacral spinal cord innervate penile vasculature and regulate penile erection. GABAergic system is involved in the regulation of male sexual behavior. Because aging is frequently accompanied by ...