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Structural characterization 1 of the jasmonoyl-isoleucine 2 perception complexes from Fragaria vesca by in silico 3 molecular analysis
(2018)
The phytohormone jasmonates (JAs) regulate fundamental plant processes; such
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as the anthocyanin accumulation during ripening of strawberry, a non-climacteric fruit model.
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Jasmonoyl-isoleucine (JA-Ile), one of the ...
Genome sequencing and genetic characterization of Culex Flavirirus (CxFV) provides new information about its genotypes
(2016-09-23)
Background: Culex Flavivirus (CxFV) is an insect-specific virus that is widely distributed and primarily infects mosquito species from the genus Culex. Its hosts include Culex tritaeniorhynchus, Culex quinquefasciatus, and ...
Comparison of Humanized IgG and FvFc Anti-CD3 Monoclonal Antibodies Expressed in CHO Cells
(HUMANA PRESS INC, 2010)
Two humanized monoclonal antibody constructs bearing the same variable regions of an anti-CD3 monoclonal antibody, whole IgG and FvFc, were expressed in CHO cells. Random and site-specific integration were used resulting ...
An efficient method for variable region assembly in the construction of scfv phage display libraries using independent strand amplification
(2012)
Phage display library technology is a common method to produce human antibodies. In this technique, the immunoglobulin variable regions are displayed in a bacteriophage in a way that each filamentous virus displays the ...
Ingeniería de anticuerpos aplicada a la generación de nuevas entidades terapéuticas antagonistas de la actividad biológica de interferón-α2b humano
(2021-07-05)
Con el objetivo de desarrollar moléculas terapéuticas capaces de neutralizar la actividad biológica (AB) del interferón alfa humano (hIFN-α), se llevó a cabo la humanización del fragmento murino scFv derivado del mAb ...