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Efeito do tratamento com Canabidiol na modulação da encefalomielite autoimune experimental
(Universidade Federal de Juiz de Fora (UFJF)BrasilICB – Instituto de Ciências BiológicasUFJF, 2023)
Mecanismos inflamatórios envolvidos na indução de febre por lipopolissacarídeo: participação da microbiota comensal, da enzima fosfatidilinositol 3-quinase gama e do receptor do fator ativador de plaquetas
(Universidade Federal de Minas GeraisUFMG, 2015-07-31)
The control of body temperature is thought to contribute to the immune system. In endothermic animals, this modulation is finely tuned by the hypothalamus, with local production of cytokines and lipid mediators. Fever is ...
Localização genômica e subcelular dos membros da família de fosfatidilinositol quinases em Trypanosoma cruzi
(Universidade Federal de São Paulo (UNIFESP), 2011-07-27)
The identification of signaling molecules and the elucidation of signal transduction processes of Trypanosoma cruzi are required for understanding the host-parasite interaction and physiological processes of the parasite. ...
Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent mechanism
(American Society for Biochemistry and Molecular Biology, 2019)
Participação da Fosfatidilinositol 3-quinase no modelo murino de infecção pelo dengue virus sorotipo 3
(Universidade Federal de Minas GeraisUFMG, 2013-02-07)
Dengue is one of the most important mosquito-borne diseases affecting humans nowadays. It has become a great concern to public health system, given the incidence of the disease caused by dengue virus (DENV) has increased ...
Papel da enzima fosfatidilinositol-3-quinase (PI3K) sobre crises convulsivas e epileptogênese em modelo animal de epilepsia induzido por pilocarpina
(Universidade Federal de Minas GeraisUFMG, 2013-03-25)
Introduction: Temporal Lobe Epilepsy (TLE) is the most common form of epilepsy in adults. The experimental model of epilepsy induced by pilocarpine (PILO) induces behavioral and pathophysiological changes in rodents very ...
Caracterização do papel da fosfatidilinositol-3 quinase γ nas respostas inflamatórias e nociceptivas induzidas pela tripsina em camundongos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2011)
This study investigated the effects of selective PI3K inhibitors in the pruriceptive, inflammatory and nociceptive responses induced by trypsin in mice. The animals were orally treated with the selective PI3Kg inhibitors ...
Caracterização do papel da fosfatidilinositol-3 quinase γ nas respostas inflamatórias e nociceptivas induzidas pela tripsina em camundongos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2011)
This study investigated the effects of selective PI3K inhibitors in the pruriceptive, inflammatory and nociceptive responses induced by trypsin in mice. The animals were orally treated with the selective PI3Kg inhibitors ...