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Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning
(Cold Spring Harbor Lab Press, 2013-10)
The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and ...
Disruptive effect of midazolam on fear memory reconsolidation: Decisive influence of reactivation time span and memory age
(Nature Publishing Group, 2009-01)
Benzodiazepine (BDZ) administered shortly after retrieval disrupts the reconsolidation of fear memory. In this research, we explored the way in which different factors that limit the emergence of such process may affect ...
A role for the interoceptive insular cortex in the consolidation of learned fear
(Elsevier B.V., 2016)
A growing body of evidence suggests that learned fear may be related to the function of the interoceptive insular cortex. Using an auditory fear conditioning paradigm in rats, we show that the inactivation of the posterior ...
A role for the interoceptive insular cortex in the consolidation of learned fear
(Elsevier B.V., 2016)
A growing body of evidence suggests that learned fear may be related to the function of the interoceptive insular cortex. Using an auditory fear conditioning paradigm in rats, we show that the inactivation of the posterior ...
Dorsolateral periaqueductal gray stimulation prior to retrieval potentiates a contextual fear memory in rats
(Elsevier Science, 2012-09)
The association of a neutral context with an aversive stimulus, such as foot-shock, result in a contextual fear memory. A growing number of evidence have revealed that prior exposure to diverse threatening situations ...
Prior stress promotes the generalization of contextual fear memories: Involvement of the gabaergic signaling within the basolateral amygdala complex
(Pergamon-Elsevier Science Ltd, 2018-04)
Fear generalization occurs when a response, previously acquired with a threatening stimulus, is transferred to a similar one. However, it could be maladaptive when stimuli that do not represent a real threat are appraised ...
Resistance to fear memory destabilization triggers exaggerated emotional-like responses following memory reactivation
(Pergamon-Elsevier Science Ltd, 2019-07)
Fear memory reactivation does not always lead to memory destabilization-reconsolidation. For instance, fear memories formed following withdrawal from chronic ethanol consumption or a stressful event are less likely to ...
The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: Influence of D-cycloserine
(Oxford University Press, 2014-01)
Background: Withdrawal from chronic ethanol facilitates the formation of contextual fear memory and delays the onset to extinction, with its retrieval promoting an increase in ethanol consumption. Consequently, manipulations ...
Inactivation of the dorsolateral periaqueductal gray matter impairs the promoting influence of stress on fear memory during retrieval
(Springer Heidelberg, 2019-11)
Exposure to stressful conditions induces long-lasting neurobiological changes in selected brain areas, which could be associated with the emergence of negative emotional responses. Moreover, the interaction of a stressful ...
On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment
(NATURE PUBLISHING GROUPLONDON, 2012)
The search for reconsolidation blockers may uncover clinically relevant drugs for disrupting memories of significant stressful life experiences, such as those underlying the posttraumatic stress disorder. Considering the ...