Apoptosis mediated by the Fas/Fas ligand (FasL) has been implicated in rejection of solid organ allografts and it has been recently proposed that soluble forms of Fas could interfere with this interaction, blocking apoptosis. ...

Gastric cancer is an important neoplastic disease in all around the world because its high incidence and mortality. Otherwise, apoptosis is a key process of programmed cell death during embryogenesis, regulation of immune ...

Introduction: We investigated the effects of apple procyanidins (Pcy), oligomers of catechins and epicatechins on Fas receptor expression and function in human colon adenocarcinoma cells (SW480) and in their derived ...

Objetivo: Estudar a participacao das moleculas Fas, FasL e Fas soluvel na reacao de rejeicao ao transplante cardiaco no homem. Metodo: a expressao de mRNA de FasL, Fas e sFas foi estudada em 21 pares de biopsias endomiocardicas ...

Human T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals ...

Increased serum soluble levels of Fas (sFas) have been reported in patients with chronic kidney disease (CKD). We sought to quantify the renal Clearance of sFas in healthy subjects and patients with CKD, to investigate ...

INTRODUÇÃO: A deficiência e a exacerbação do sistema Fas/FasL está associada ao aparecimento de diversas doenças hematológicas ou não. Na HPN, existem evidências de que o sistema Fas/FasL possa atuar na seleção e ...

Apoptosis is the major component of programmed cell death, an essential process in embryogenesis, tissue turnover and proper function of the immune system. Lack of appropriate control is thought to play an important role ...