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TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi
(Elsevier Science, 2006-01)
Cyclic nucleotide phosphodiesterases constitute the only known mechanism to inactivate regulatory signals involving cAMP or cGMP. In our laboratory a cAMP-specific phosphodiesterase associated to the flagellar apparatus, ...
Evolutionary insights into FYVE and PHOX effector proteins from the moss Physcomitrella patens
(Springer, 2020-02-10)
Phosphatidylinositol 3-phosphate (PtdIns3P) is a signaling phospholipid, which regulates several aspects of plant growth and development, as well as responses to biotic and abiotic stresses. The mechanistic insights ...
Evolutionary insights into FYVE and PHOX effector proteins from the moss Physcomitrella patens
(Springer, 2020-02)
Phosphatidylinositol 3-phosphate (PtdIns3P) is a signaling phospholipid, which regulates several aspects of plant growth and development, as well as responses to biotic and abiotic stresses. The mechanistic insights ...
The actin cytoskeleton participates in the early events of autophagosome formation upon starvation induced autophagy
(Landes Bioscience, 2012-08-06)
Autophagy is a process by which cytoplasmic material is sequestered in a double-membrane vesicle destined for degradation. Nutrient deprivation stimulates the pathway and the number of autophagosomes in the cell increases ...