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Avaliações imunogenéticas do desenvolvimento de anticorpos inibidores do fator VIII na hemofilia A
(Universidade Federal de Minas GeraisUFMG, 2010-04-19)
Hemophilia A (HA) is a coagulopaty with hereditary transmission linked to Xchromosome resulting in a deficiency or a defect in coagulation factor VIII (FVIII). Subjects with this coagulopaty need constant FVIII infusions ...
Cytokine profile and FVIII inhibitors development in haemophilia A
(Blackwell Science, 2018)
IgG subclasses of FVIII inhibitors in an argentine cohort of severe hemophilia A patients: Analysis by flow cytometry
(Wiley Blackwell Publishing, Inc, 2017-06)
FVIII inhibitors consist of a polyclonal population of antibodies. Previous studies have demonstrated different distribution of IgG subclasses. IgG4 was associated to high level of FVIII inhibitors and failure of Immune ...
Avaliação do efeito das infusões de fator VIII sobre biomarcadores imunológicos em crianças com hemofilia A
(Universidade Federal de Minas GeraisBrasilMEDICINA - FACULDADE DE MEDICINAPrograma de Pós-Graduação em Ciências Aplicadas à Saúde do AdultoUFMG, 2019-08-01)
Hemophilia A (HA) is an inherited bleeding disorder caused by factor (F)VIII deficiency. Its treatment is based on the replacement of deficient FVIII either prophylactically or on demand. One of the major complications of ...