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Development and validation of a method for the determination of folic acid in different pharmaceutical formulations using derivative spectrophotometry
(2016-10-01)
Folic acid is a B complex water-soluble vitamin that is essential to humans, and its deficiency can cause problems including congenital malformations in the fetus as well as heart disease. Most countries affected by diseases ...
Folate and Pregnancy, current concepts. It is required folic acid supplementation ?
(Sociedad Chilena de Pediatría, 2017)
Folate intake during pregnancy is essential for an adequate fetal and placental development, as well as for the long-term health condition. Because folate deficiency may induce fetal pathologies, including neural tube ...
Folato Sérico y Eritrocitario en el Lactante
(Sociedad Chilena de Pediatría, 1983)
Neural tube defects prevalence does not increase aftermodification of the folic acid fortification program in Chile
(2022)
Background:In 2000, Chile’s Ministry of Health mandated fortification ofwheat flour with folic acid at a concentration of 2.2 mg/kg to prevent neuraltube defects (NTDs), resulting in a 50% reduction in NTD prevalence. ...
Natural killer cell cytotoxicity is not regulated by folic acid in vitro
(Elsevier, 2013)
Objectives: Folate supplementation may be associated with an increased risk of developing several
types of cancer and a derangement of immune function.Among the latter, Natural killer (NK) cells are
involved in ...
Bioaccessibility of folic acid in egg white nanocarriers and protein digestion profile in solution and in emulsion
(Elsevier Science, 2019-08)
The objective of this work is to assess bioaccessibility of folic acid in egg white (EW) nanocarriers after digestion of solutions and emulsions containing the vitamin-protein complexes. Furthermore, the influence of folic ...
Sister-chromatid exchanges in β-thalassaemic patients under conditions of in vivo and in vitro depletion of folic acid
(1992-07-02)
In order to investigate the effect of folate depletion, lymphocyte sister-chromatid exchange (SCE) rates were compared among homozygous β-thalassaemic patients with low folic acid levels, heterozygous β-thalassaemic patients ...