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Avaliação morfométrica e estereométrica dos tecidos periodontais de ratos imunossuprimidos por Tracolimus (FK506)
(Universidade Estadual Paulista (UNESP), 2014)
Avaliação morfométrica e estereométrica dos tecidos periodontais de ratos imunossuprimidos por Tracolimus (FK506)
(Universidade Estadual Paulista (Unesp), 2006-02-15)
Tacrolimus (FK506) é uma droga imunossupressora usada em transplantes de órgãos e também como terapia alternativa em pacientes com rejeição refratária de enxertos ou intolerância à ciclosporina A (CsA), sem os efeitos ...
Neuroprotective effect of FK506 against oxidative stress
(Sociedad Argentina de Neurociencias, 2020)
Immunosuppressant Prograf (R) (Tacrolimus) Induces Histopathological Disorders in the Peritubular Tissue of Rat Testes
(Karger, 2011-01-01)
Treatment with tacrolimus (FK-506) has been shown to induce a significant decrease in the number of spermatocytes, spermatids, and Sertoli cells. Regarding the importance of the peritubular tissue for the maintenance of ...
Immunosuppressant Prograf (R) (Tacrolimus) Induces Histopathological Disorders in the Peritubular Tissue of Rat Testes
(Karger, 2011-01-01)
Treatment with tacrolimus (FK-506) has been shown to induce a significant decrease in the number of spermatocytes, spermatids, and Sertoli cells. Regarding the importance of the peritubular tissue for the maintenance of ...
Neuroregenerative and neuroprotective actions of immunophilin ligands in murine models
(Fundación Revista Medicina, 2017)
Immunophilins (IMMs) are a family of intracellular proteins that bind immunosuppressive drugs. They are referred to as FK506-binding proteins (FKBPs) when they bind FK506, and cyclophilins (CyPs) when they bind cyclosporine ...
Avaliação morfométrica e estereométrica dos tecidos periodontais de ratos imunossuprimidos por Tracolimus (FK506)
(Universidade Estadual Paulista (Unesp), 2014)
Phosphorylation of Ryanodine Receptors
(Sociedad de Biología de Chile, 2004)
Proof that the high molecular weight immunophilin FKBP52 mediates the in vivo neuroregenerative effect of the macrolide FK506
(Pergamon-Elsevier Science Ltd, 2020-12)
The immunosuppressant drug FK506 (or tacrolimus) is a macrolide that binds selectively to immunophilins belonging to the FK506-binding protein (FKBP) subfamily, which are abundantly expressed proteins in neurons of the ...
Changes in lymphocyte phenotype and increased skin allograft survival after FTY720+FK506 therapy
(Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2008-01-01)
The development of new drugs to be associated with calcineurin inhibitors and promote additional immunosuppression with fewer side effects is the goal in transplantation. FTY720 is a new synthetic compound which presents ...