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First-line methadone for cancer pain: titration time analysis
(Springer, 2021-04)
Background: Methadone is a low-cost, strong opioid that is increasingly used as a first-line treatment for pain in palliative care (PC). Its long and unpredictable half-life and slow elimination phase can make titration ...
Methadone as first-line opioid treatment for cancer pain in a developing country palliative care unit
(Springer, 2016-08)
Purpose: The use of methadone for cancer pain is limited by the need of expertise and close titration due to variable half-life. Yet, it is a helpful palliative strategy in low-resources countries given its long-acting ...