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Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems
(2021-08-01)
Nanotechnology has been widely applied to develop drug delivery systems to improve therapeutic performance. The effectiveness of these systems is intrinsically related to their physicochemical properties, so their biological ...
Systematic sequencing of factorial experiments as an alternative to the random order
(2017-01-01)
The current study aims to discuss the use of systematic methods to generate experimental designs with good statistical properties and low costs. The research focuses on the sequence of experiments and on analysis the results ...
Application of Factorial Design Experiments to the Development of a Disposable Amperometric DNA Biosensor
(Wiley-v C H Verlag Gmbh, 2011-11-01)
The development of an amperometric DNA-based biosensor (genosensor) requires the optimization of many experimental parameters in order to maximize sensitivity. If only one parameter is evaluated per experiment, the resultant ...
Application of Factorial Design Experiments to the Development of a Disposable Amperometric DNA Biosensor
(Wiley-v C H Verlag Gmbh, 2011-11-01)
The development of an amperometric DNA-based biosensor (genosensor) requires the optimization of many experimental parameters in order to maximize sensitivity. If only one parameter is evaluated per experiment, the resultant ...
Fundamental concepts and recent applications of factorial statistical designs
(Universidade Federal de Lavras (UFLA), 2022-03-04)
Factorial designs have been increasingly used in scientific investigations and technological development. The designs, through the use of matrices with all the treatment combinations, have been capable to effectively ...
FUNDAMENTAL CONCEPTS AND RECENT APPLICATIONS OF FACTORIAL STATISTICAL DESIGNS
(2022-03-04)
Factorial designs have been increasingly used in scientific investigations and technological development. The designs, through the use of matrices with all the treatment combinations, have been capable to effectively ...
Use of Factorial Designs and the Response Surface Methodology to Optimize a Heat Staking Process
(2018-06-01)
The demand from the automotive industry for lighter and more resistant structures produced at lower costs has shifted the development focus of production processes toward hybrid components. A problem that arises from hybrid ...
Optimization of an amperometric biosensor for the detection of hepatitis C virus using fractional factorial designs
(Soc Brasileira Quimica, 2008-01-01)
Fractional factorial design and factorial with center point design were applied to the development of an amperometric biosensor for the detection of the hepatitis C virus. Biomolecules were immobilized by adsorption on ...
Optimization of an amperometric biosensor for the detection of hepatitis C virus using fractional factorial designs
(Soc Brasileira Quimica, 2008-01-01)
Fractional factorial design and factorial with center point design were applied to the development of an amperometric biosensor for the detection of the hepatitis C virus. Biomolecules were immobilized by adsorption on ...
Optimum design of experiments for statistical inference
(Wiley-Blackwell, 2012-01-01)
. One attractive feature of optimum design criteria, such as D- and A-optimality, is that they are directly related to statistically interpretable properties of the designs that are obtained, such as minimizing the volume ...