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Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis
(BMC, 2019)
BackgroundAmyotrophic lateral sclerosis (ALS) is a multifactorial fatal motoneuron disease without a cure. Ten percent of ALS cases can be pointed to a clear genetic cause, while the remaining 90% is classified as sporadic. ...
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis
(ELSEVIER SCIENCE INC, 2018)
The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia
(Humana Press, 2018)
Sensory neurons from dorsal root ganglion efficiently regenerate after peripheral nerve injuries. These neurons are widely used as a model system to study degenerative mechanisms of the soma and axons, as well as regenerative ...
Accidents with biological material: an approach based on the analysis of work activities
(Univ Sao Paulo, Fac Saude Publica, 2015-10-01)
The present qualitative study was carried out in a university hospital, with the purpose of analyzing the work of nursing assistants and technicians, the numerous category among health profess als and more prone to accidents ...
Seasonality Analysis of Sentinel-1 and ALOS-2/PALSAR-2 Backscattered Power over Salar de Aguas Calientes Sur, Chile
(MDPI Multidisciplinary Digital Publishing Institute, 2020-03)
Seasonal changes control the development of salt crust over the Salar de Aguas Calientes Sur located in Andes Highlands, Chile. Precipitations throughout the Altiplanic winter (December to March) and austral winter (June ...
Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
(Karger, 2017)
Background: The growth-promoting effects of IGF-I is mediated through the IGF-I receptor (IGF1R), a widely expressed cell-surface tyrosine kinase receptor. IGF1R copy number variants (CNV) can cause pre- and postnatal ...
Characteristics and motivations of donors to the human milk ba nk in Dr. Sotero del Rio Hospital, Chile
(SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2020)
This study sought to describe characteristics, motivations, barriers, and sources of information of human milk donors to the milk bank at Dr. Sotero del Rio Hospital, Chile. Methods: A descriptive and cross - sectional ...
Axonal Degeneration Is Mediated by Necroptosis Activation
(SOC NEUROSCIENCE, 2019-05-15)
Axonal degeneration, which contributes to functional impairment in several disorders of the nervous system, is an important target for neuroprotection. Several individual factors and subcellular events have been implicated ...
KINEMATIC ANALYSIS OF THE RONDAT FLIC-FLAC
(UNIV MALAGA, 2019)
The objective of the present article is to show an analysis of the kinetic and cinematic indicators of Rondat flic-flac exercise. A qualitative and systematic research of the corresponding literature of the last twenty ...