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Inositol trisphosphate and excitation-contraction coupling in skeletal muscle
(Kluwer Academic Publishers-Plenum Publishers, 1989)
The role of inositol trisphosphate as a chemical messenger in excitation-contraction coupling is discussed, both in terms of positive and negative results. The evidence presented includes experiments on the effect of ...
Preserved Ca2+ handling and excitation-contraction coupling in muscle fibres from diet-induced obese mice
(Springer, 2020)
Aims/hypothesis Disrupted intracellular Ca2+ handling is known to play a role in diabetic cardiomyopathy but it has also been
postulated to contribute to obesity- and type 2 diabetes-associated skeletal muscle dysfunction. ...
Membrane Cholesterol in Skeletal Muscle: A Novel Player in Excitation-Contraction Coupling and Insulin Resistance
(Hindawi Limited, 2017)
© 2017 G. Barrientos et al.Membrane cholesterol is critical for signaling processes in a variety of tissues. We will address here current evidence supporting an emerging role of cholesterol on excitation-contraction coupling ...
Functional muscarinic receptors in cultured skeletal muscle
(Academic Press Inc., 1996)
We studied the influence of muscarinic and nicotinic stimulation on both phosphoinositide metabolism and intracellular calcium levels in rat skeletal muscle primary cultures. Both nicotine and muscarine induced an increase ...
Effects of change in temperature on the cardiac contractility of broad-snouted caiman (Caiman latirostris) during digestion
(2021-04-01)
In many reptiles, digestion has been associated with the selection of higher body temperatures, the so-called post-prandial thermophilic response. This study aimed to investigate the excitation–contraction (E–C) coupling ...
Cholesterol removal from adult skeletal muscle impairs excitation–contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins
(2015)
Cholesterol and caveolin are integral membrane components that modulate the function/location of many cellular proteins. Skeletal muscle fibers, which have unusually high cholesterol levels in transverse tubules, express ...
Phosphorylation of phosphatidylinositol by transverse tubule vesicles and its possible role in excitation-contraction coupling
(1986)
Phosphorylation of phosphatidylinositol to phosphatidylinositol 4-monophosphate and to phosphatidyl-inositol 4,5-bisphosphate was demonstrated in transverse-tubule membranes isolated from frog skeletal muscle using [γ-32P]ATP ...