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Concomitant stress potentiates the preference for, and consumption of, ethanol induced by chronic pre-exposure to ethanol
(2016-01-01)
Ethanol abuse is linked to several acute and chronic injuries that can lead to health problems. Ethanol addiction is one of the most severe diseases linked to the abuse of this drug. Symptoms of ethanol addiction include ...
Endothelial AT(1) and AT(2) pathways in aortic responses to angiotensin II after stress and ethanol consumption in rats
(Informa Healthcare, 2014-12-01)
Stress and ethanol are important cardiovascular risk factors. Their vascular and blood pressure (BP) effects were evaluated alone and in combination. Adult male Wistar rats (8-10 per group) were separated into control, ...
Age-related effects of chronic restraint stress on ethanol drinking, ethanol-induced sedation, and on basal and stress-induced anxiety response
(Elsevier Science Inc, 2016-03)
Adolescents are sensitive to the anxiolytic effect of ethanol, and evidence suggests that they may be more sensitive to stress than adults. Relatively little is known, however, about age-related differences in stress ...
Genetic and environmental influences on ethanol consumption: Perspectives from preclinical research
(Blackwell Publishing Ltd, 2010)
Background: Alcohol use disorders (abuse and dependence, AUD) are multifactorial phenomena, depending on the interplay of environmental and genetic variables. Method: This review describes current developments in animal ...
Age-dependent effects of ethanol and stress on acute motor activity in rats
(Springer, 2013-06)
Rationale: It is important to study age-related differences that may put adolescents at risk for alcohol-related problems. Adolescents seem less sensitive to the aversive effects of ethanol than adults. Less is known of ...
Individual differences predictive of ethanol-induced reinforcement and ethanol intake during adolescence
(2013)
Likelihood of alcohol use disorders is greater in adolescence than in other developmental stages. Greater novelty-seeking, enhanced sensitivity to stress or to ethanol-induced appetitive effects, or lessened sensitivity ...
Restraint stress exacerbates cell degeneration induced by acute binge ethanol in the adolescent, but not in the adult or middle-aged, brain
(Elsevier Science, 2019-02)
Restraint stress (RS) induces neurotoxicity in the hippocampus, yet most of the studies have employed protracted RS (i.e., ≈ 21 days). Binge ethanol can induce brain toxicity, an effect affected by age. It could be postulated ...
Stress Abolishes the Effect of Previous Chronic Ethanol Consumption on Drug Place Preference and on the Mesocorticolimbic Brain Pathway
(Wiley-Blackwell, 2014-05-01)
BackgroundConditioned place preference (CPP) to ethanol (EtOH) is an important addiction-related alteration thought to be mediated by changed neurotransmission in the mesocorticolimbic brain pathway. Stress is a factor of ...