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Place conditioning with ethanol in rats bred for high (UChB) and low (UChA) voluntary alcohol drinking
(2011)
The main goal of this study was to investigate the ability of an ethanol dose (1. g/kg) administered intraperitoneally to induce conditioned place preference (CPP) and/or conditioned place aversion (CPA) in two lines of ...
Ethanol pre-exposure during adolescence or adulthood increases ethanol intake but ethanol-induced conditioned place preference is enhanced only when pre-exposure occurs in adolescence
(Wiley InterscienceNew York, 2014-01)
Behavioral sensitization has been suggested to contribute to uncontrolled alcohol consumption. The aim of this study was to investigate the effects of repeated ethanol administration in adolescent and adult mice on subsequent ...
Ethanol-induced locomotor activity in adolescent rats and the relationship with ethanol-induced conditioned place preference and conditioned taste aversion
(Wiley, 2012-05)
Adolescent rats exhibit ethanol-induced locomotor activity (LMA), which is considered an index of ethanol's motivational properties likely to predict ethanol self-administration, but few studies have reported or correlated ...
Nicotine affects ethanol-conditioned taste, but not place, aversion in a simultaneous conditioning procedure
(Elsevier Science Inc, 2018-09)
The conditioned taste aversion (CTA) induced by ethanol is a key factor limiting ethanol intake. Nicotine, a drug co-consumed with ethanol, may decrease this aversion by modulating the unconditioned effects of ethanol or ...
Susceptibility to extinction and reinstatement of ethanol-induced conditioned place preference is related to differences in astrocyte cystine-glutamate antiporter content
(2020-01-01)
Individual susceptibility to alcohol effects plays an important role in the development of alcohol addiction and studies have shown that glutamate release is altered after chronic ethanol consumption. The cystine-glutamate ...
Conessine, an H3 receptor antagonist, alters behavioral and neurochemical effects of ethanol in mice
(2016-05-15)
Ethanol abuse potential is mainly due to its reinforcing properties, crucial in the transition from the recreational to pathological use. These properties are mediated by mesocorticolimbic and nigrostriatal dopaminergic ...
Individual differences predictive of ethanol-induced reinforcement and ethanol intake during adolescence
(2013)
Likelihood of alcohol use disorders is greater in adolescence than in other developmental stages. Greater novelty-seeking, enhanced sensitivity to stress or to ethanol-induced appetitive effects, or lessened sensitivity ...
Short and prolonged maternal separation impacts on ethanol-related behaviors in rats: sex and age differences
(2019-01-01)
Maternal separation (MS) is an animal model widely used to evaluate the influence of early-life stress exposure on ethanol consumption and dependence. The goal of this study was to evaluate the effects of brief and prolonged ...
Stress Abolishes the Effect of Previous Chronic Ethanol Consumption on Drug Place Preference and on the Mesocorticolimbic Brain Pathway
(Wiley-Blackwell, 2014-05-01)
BackgroundConditioned place preference (CPP) to ethanol (EtOH) is an important addiction-related alteration thought to be mediated by changed neurotransmission in the mesocorticolimbic brain pathway. Stress is a factor of ...
Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice
(Nature Publishing Group, 2017-12-17)
Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs. adult (mice) differences in the ...