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Mechanism and effect of esculetin in an experimental animal model of inflammatory bowel disease
(2013-05-01)
Esculetin is a coumarin derivative with high antioxidant activity. In a rat experimental model of inflammatory bowel disease induced by trinitrobenzenesulfonic acid, esculetin at the dose of 5mg/Kg displayed intestinal ...
Mechanism and effect of esculetin in an experimental animal model of inflammatory bowel disease
(2013-05-01)
Esculetin is a coumarin derivative with high antioxidant activity. In a rat experimental model of inflammatory bowel disease induced by trinitrobenzenesulfonic acid, esculetin at the dose of 5mg/Kg displayed intestinal ...
Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis
(Elsevier B.V., 2010-07-30)
Coumarins comprise a broad class of phenolic compounds that influences the formation and scavenging of reactive oxygen species and the processes involving free radical-mediated injury. In light of the antioxidant and ...
Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis
(Elsevier B.V., 2010-07-30)
Coumarins comprise a broad class of phenolic compounds that influences the formation and scavenging of reactive oxygen species and the processes involving free radical-mediated injury. In light of the antioxidant and ...
Coumarins of haplopappus multifolius and derivative as inhibitors of lox: Evaluation in-vitro and docking studies
(Sociedad Chilena de Quimica, 2013)
Several natural compounds containing a coumarin moiety have been reported. They have multiple biological activities, e. g. , as scavengers of reactive oxygen species (ROS) and to reduce the inflammatory processes by ...
Study of the action of Flavonoids on Xanthine-Oxidase by molecular topology
(American Chemical Society, 2000-06-01)
A study was performed on xanthine-oxidase inhibition by 22 flavonoids, including flavones, flavonols, flavanones, and chalcones, using UV spectroscopy for experimental data and molecular topology to establish the ...
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling.
(2015)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which pathogenesis and death of motor neurons are triggered by non-cell-autonomous mechanisms. We showed earlier that exposing primary rat spinal ...
Oxidation of ethanol to acetaldehyde and free radicals by rat testicular microsomes
(Springer, 2005-01)
A large number of epidemiological studies evidencing that excessive alcohol consumption is associated with impaired testosterone production and testicular atrophy are available in the literature. One hypothesis to explain ...