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Social defeat stress in rats: escalation of cocaine and speedball binge self-administration, but not heroin
(Springer, 2011-05-01)
Exposure to intermittent episodes of social defeat stress can increase drug seeking and leads to intense drug taking in rats.This study investigated the consequences of repeated, intermittent social defeat stress on patterns ...
Prevention of social stress-escalated cocaine self-administration by CRF-R1 antagonist in the rat VTA
(Springer, 2011-11-01)
Intermittent exposure to social defeat stress can induce long-term neural plasticity that may influence escalated cocaine-taking behavior. Stressful encounters can lead to activation of dopamine neurons in the ventral ...
Prevention of social stress-escalated cocaine self-administration by CRF-R1 antagonist in the rat VTA
(Springer, 2011-11-01)
Intermittent exposure to social defeat stress can induce long-term neural plasticity that may influence escalated cocaine-taking behavior. Stressful encounters can lead to activation of dopamine neurons in the ventral ...
Social defeat stress in rats: escalation of cocaine and speedball binge self-administration, but not heroin
(Springer, 2011-05-01)
Exposure to intermittent episodes of social defeat stress can increase drug seeking and leads to intense drug taking in rats.This study investigated the consequences of repeated, intermittent social defeat stress on patterns ...
Avaliação de alterações na cascata intracelular de sinalização dopaminérgica no núcleo accumbens relacionadas com a escalada da autoadministração de cocaína em ratos
(Universidade Federal de São Paulo, 2023-07-11)
A cocaína é uma das drogas ilícitas mais utilizadas mundialmente e seu uso vem aumentando nos últimos anos. Quando utilizada repetidamente, essa substância pode causar dependência, o que pode ocasionar consequências adversas ...
Mecanismos comportamentais e moleculares envolvidos na interação entre as substâncias de abuso e os fatores de risco para o desenvolvimento da dependência
(Universidade Federal de São CarlosBRUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, 2013-03-08)
Tobacco and ethanol are the most used drugs in the world and often co-abused. An important issue in the field of drug abuse research is the characterization of risk factors related to increased vulnerability to drug ...