Now showing items 1-10 of 218
Differential effect of erythropoietin and carbamylated erythropoietin on endothelial cell migration
(Pergamon-Elsevier Science Ltd, 2017-04)
Protein tyrosine phosphatase 1B (PTP1B) is involved in the defective erythropoietic function of carbamylated erythropoietin
(Pergamon-Elsevier Science Ltd, 2015-02)
• Epo induced prolonged phosphorylation of proliferation signals in UT-7 cells. • cEpo induced only transient phosphorylation of proliferative pathways. • PTP1B activity was significantly increased in cultures with cEpo. ...
Erythropoietin induces bone marrow and plasma fibroblast growth factor 23 during acute kidney injury
It is accepted that osteoblasts/osteocytes are the major source for circulating fibroblast growth factor 23 (FGF23). However, erythropoietic cells of bone marrow also express FGF23. The modulation of FGF23 expression in ...
Use of intravenous iron without erythropoietin for the treatment of anemia of hemodialysis Corrección de la anemia en hemodiálisis, efecto del fierro intravenoso sin eritropoyetina
Background: In the last two decades, the use of erythropoietin for the correction of anemia in hemodialysis patients has been recommended. In Chile, only 10% of hemodialysis patients use erythropoietin, therefore, the ...
Signaling pathways of cell proliferation are involved in the differential effect of erythropoietin and its carbamylated derivative
(Elsevier Science, 2013-08)
It is now recognized that in addition to its activity upon erythroid progenitor cells, erythropoietin (Epo) is capable of stimulating survival of different non-erythroid cells. Since stimulation of erythropoiesis is unwanted ...
Erythropoietin and the polycythemia of high-altitude wellers
(Molecular Biology of Erythropoiesis, 1989)
Abstract High-altitude natives residing at similar altitudes exhibit varying degrees of erythrocytosis, depending in part upon their geographical location. A recent report by Winslow et al suggests that hematocrit and ...
Erythropoietin and the use of a transgenic model of erythropoietin-deficient mice
(Dove Medical Press, 2016)
Despite its well-known role in red blood cell production, it is now accepted that erythropoietin (Epo) has other physiological functions. Epo and its receptors are expressed in many tissues, such as the brain and heart. ...
Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly
(American Physiological Society, 2015)
Under conditions of accelerated erythropoiesis, elevated erythropoietin (Epo) levels are associated with inhibition of hepcidin synthesis, a response that ultimately increases iron availability to meet the enhanced iron ...