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Uterine ERα epigenetic modifications are induced by the endocrine disruptor endosulfan in female rats with impaired fertility
(Elsevier Ireland, 2017-10)
High ERα activity may disrupt the window of uterine receptivity, causing defective implantation. We investigated whether implantation failures prompted by endosulfan are associated with aberrant ERα uterine expression and ...
Análise energética in silico das interações: ERα-Tamoxifeno, ERα- Raloxifeno e Integrina αVβ3-Cilengitide
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM DESENVOLVIMENTO E INOVAÇÃO TECNOLÓGICA EM MEDICAMENTOS, 2016-10-07)
This thesis deals with two researches with different conceptual nature in the field of molecular modeling based on similar theoretical principles of quantum physics and computational chemistry. In the first study the ...
Expression of estrogen receptor α variants and c-Fos in rat mammary gland and tumors
(Pergamon-Elsevier Science Ltd, 2020-01)
Breast cancer is currently the leading cause of cancer death among women worldwide. AP-1 (c-Fos/c-Jun) isassociated with proliferation and survival, while cytoplasmic c-Fos activates phospholipid synthesis in cellsinduced ...
Eficacia pronóstica de la determinación de los receptoresmoleculares ERα y Her2-neu en tumores mamarios caninosPredictive effectiveness of the determination of two molecular receptors ERα and Her2-neu in canine mammary tumors
(Universidad Nacional del Nordeste. Facultad de Ciencias VeterinariasRevista Veterinaria, 2011-07-01)
El objetivo del presente trabajo fue resaltar el valor que representa la determinación de receptores de estrógeno alfa (Erα) y del receptor tipo 2 del factor de crecimiento epitelial (Her2-neu) en los tumores mamarios, ...
The ERα membrane pool modulates the proliferation of pituitary tumours
(BioScientifica, 2019-02)
The molecular mechanisms underlying the ERα nuclear/cytoplasmic pool that modulates pituitary cell proliferation have been widely described, but it is still not clear how ERα is targeted to the plasma membrane. The aim of ...
Eficacia pronóstica de la determinación de los receptoresmoleculares ERα y Her2-neu en tumores mamarios caninos
(Universidad Nacional del Nordeste, 2011)
Circadian variations in the expression of estrogen receptor alfa in retina of viscacha
(Instituto de Histología y Embriología, 2019)
In some species the presence of estrogen receptors α (ERα) has been demonstrated in retina. ERα are involved in neuroprotectivefunctions through their ability to regulate apoptosis, autophagy and antioxidant processes. ...
Inverse association between estrogen receptor-α DNA methylation and breast composition in adolescent Chilean girls
(2018)
Abstract
Background
Estrogen receptor-α (ER-α) is a transcriptional regulator, which mediates estrogen-dependent breast development, as well as breast tumorigenesis. The ...