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Evaluación de la capacidad inmunogénica de epítopes transplantados en la superficie de proteínas séricas: hacia el desarrollo de nuevas vacunas epitópicas
(Universidad Peruana Cayetano HerediaPE, 2022)
Las vacunas más importantes en la actualidad las constituyen principalmente proteínas recombinantes, las cuales se caracterizan por una rápida degradación y corto tiempo de circulación, por lo que su exposición al sistema ...
A comparative in silico linear B-cell epitope prediction and characterization for South American and African Trypanosoma vivax strains
(2018-01-01)
Trypanosoma vivax is a parasite widespread across Africa and South America. Immunological methods using recombinant antigens have been developed aiming at specific and sensitive detection of infections caused by T. vivax. ...
Theoretical analysis of the neuraminidase epitope of the Mexican A H1N1 influenza strain, and experimental studies on its interaction with rabbit and human hosts
(Springer, 2013)
The neuraminidase (NA) epitope from the Mexican AH1N1 influenza virus was identified by using sequences registered at the GenBank during the peak of a pandemic (from April 2009 to October 2010). First, NA protein sequences ...
In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine
(Elsevier, 2018-04)
Background: Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane ...
Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom
(2012)
Knowledge on toxin immunogenicity at the molecular level can provide valuable information
for the improvement of antivenoms, as well as for understanding toxin structure–
function relationships. The aims of this study ...
Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom
(2012)
Knowledge on toxin immunogenicity at the molecular level can provide valuable information
for the improvement of antivenoms, as well as for understanding toxin structure–
function relationships. The aims of this study ...
Evaluation and Comparison of the Ability of Online Available Prediction Programs to Predict True Linear B-cell Epitopes
(Bentham Science Publishers, 2013-06)
This work deals with the use of predictors to identify useful B-cell linear epitopes to develop immunoassays. Experimental techniques to meet this goal are quite expensive and time consuming. Therefore, we tested 5 free, ...