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Endothelin-converting enzyme-1c promotes stem cell traits and aggressiveness in colorectal cancer cells
(John Wiley and Sons Ltd., 2020-02)
Endothelin-1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin-1 rely on its activation by endothelin-converting enzyme-1 (ECE1), which is expressed ...
Endothelin-1 attenuates bradykinin-induced hypotension in rats
(Elsevier Science BvAmsterdamHolanda, 2000)
Endothelin-converting enzyme-1c promotes stem cell traits and aggressiveness in colorectal cancer cells
(Facultad de Medicina y CienciaCentro de Biología Celular y Biomedicina CEBICEM, 2020)
Endothelin-1 is a mitogenic peptide that activates several proliferation, survival, and invasiveness pathways. The effects of endothelin-1 rely on its activation by endothelin-converting enzyme-1 (ECE1), which is expressed ...
Localization of the endothelin system in aldosterone-producing adenomas
(Lippincott Williams, 2001-11-01)
Endothelin-1 (ET-1) could play a role in the regulation of aldosterone secretion of the human adrenal gland. The presence of the endothelin-converting enzyme 1 (ECE-1) and ET-1 suggests that there is a local ET system in ...
Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability
(Impact Journals LLC, 2015)
Endothelin-converting enzyme-1c (ECE-1c) is a membrane metalloprotease involved in endothelin-1 synthesis, which has been shown in vitro to have a role in breast, ovary and prostate cancer cell invasion. N-terminal end of ...
Effects of experimental intracerebral ventricular injection of amyloid beta peptide (1-42) aggregates on daily rhythms of Aβ-degrading enzymes in the hippocampus: Relevance to Alzheimer's disease pathophysiology
(Elsevier, 2019-09)
One of the main pathological features in the Alzheimer disease (AD) is the presence of senile plaques, primarily composed of Aβ peptide aggregates, in cortex and hippocampus. AD late onset, which constitutes 90% of cases, ...
Endothelin-converting enzyme-1 in cancer aggressiveness
(Elsevier Ireland Ltd, 2019)
The endothelin-1 (ET-1) axis contributes to the pathophysiology of several cancers by promoting tumor development and progression. This peptide is activated from its precursor, big ET-1, by endothelin-converting enzyme-1 ...