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Opening of Cx43-formed hemichannels mediates the Ca2+ signaling associated with endothelial cell migration
(BioMed Central Ltd, 2023)
© 2023, BioMed Central Ltd., part of Springer Nature.Endothelial cell migration is a key process in angiogenesis. Progress of endothelial cell migration is orchestrated by coordinated generation of Ca2+ signals through a ...
Pediatric corneal transplants
(Lippincott Williams & Wilkins, 2017)
Purpose of reviewPediatric keratoplasty poses unique challenges in clinical and surgical management. However, successful transplantation can afford a child vision in an otherwise poorly seeing eye. This review will provide ...
Targeting the Endothelium to Achieve Cardioprotection
(Frontiers Media, 2021)
Despite considerable improvements in the treatment of myocardial infarction, it is still a highly prevalent disease worldwide. Novel therapeutic strategies to limit infarct size are required to protect myocardial function ...
Preeclamptic plasma stimulates the expression of miRNAs, leading to a decrease in endothelin-1 production in endothelial cells
(Elsevier B.V., 2018-04-01)
Preeclampsia is a major cause of maternal and fetal morbidity and mortality worldwide. It is a multisystem pregnancy syndrome characterized by general endothelial dysfunction caused mainly by plasma factors and debris in ...
In vivo vascular rarefaction and hypertension induced by dexamethasone are related to phosphatase PTP1B activation not endothelial metabolic changes
(2020-05-20)
Glucocorticoids have important anti-inflammatory and immunomodulatory activities. Dexamethasone (Dex), a synthetic glucocorticoid, induces insulin resistance, hyperglycemia, and hypertension. The hypertensive mechanisms ...
A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide
(John Wiley & Sons Ltd, 2009-05)
Background: Targeted gene transduction in vivo is the ultimate preferred method for gene delivery. We previously developed targeting lentiviral vectors that specifically recognize cell surface molecules with conjugated ...