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Estudo da interação molecular de retrovírus endógenos humanos e antígenos da mielina com anticorpos
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Biotecnologia e Monitoramento Ambiental - PPGBMA-SoCâmpus Sorocaba, 2018-02-26)
Multiple sclerosis (MS) is an inflammatory, demyelinating and autoimmune disease of the central nervous system. There is evidence that demyelination may be related to the production of autoreactive antibodies against myelin ...
Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
(2016-06-16)
Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still ...
Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
(2016-06-16)
Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still ...
Human endogenous retrovirus: their relationship with hematological diseases
(Longdom Group, 2016)
Human endogenous retrovirus (HERVs) integrated in the human genome millions of years ago and became astable part of the inherited genetic material. Most of these HERVs are dysfunctional due to numerous mutations andthus ...
Genomic analysis of ERVWE2 locus in patients with multiple sclerosis: absence of genetic association but potential role of human endogenous retrovirus type W elements in molecular mimicry with myelin antigen
(FrontiersLausanne, 2013-06)
Human endogenous retroviruses (HERVs) arise from ancient infections of the host germline cells by exogenous retroviruses, constituting 8% of the human genome. Elevated level of envelope transcripts from HERVs-W has been ...
Human Endogenous Retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods
(, 2013)
Abstract
Background
An estimated 10–20 million individuals are infected with the retrovirus human T-cell leukemia virus type ...