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El sistema endocanabinoide y su función en los animales
(Universidad Autónoma del Estado de México, 2019)
Endocannabinoids, Through Opioids And Prostaglandins, Contribute To Fever Induced By Key Pyrogenic Mediators
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2016)
The endocannabinoid anandamide during lactation increases body fat content and CB1 receptor levels in mice adipose tissue
(Nature Publishing, 2015)
Type 1 cannabinoid receptors (CB1R) modulate energy balance; thus, their premature activation may result in altered physiology of tissues involved in such a function. Activation of CB1R mainly occurs after binding to the ...
Novel endogenous peptide agonists of cannabinoid receptors
(FEDERATION AMER SOC EXP BIOL, 2009)
Hemopressin (Hp), a 9-residue alpha-hemoglobin-derived peptide, was previously reported to function as a CB(1) cannabinoid receptor antagonist (1). In this study, we report that mass spectrometry (MS) data from peptidomics ...
Endocannabinoid system in pregnancy
(BioScientifica, 2016-12)
The endocannabinoid system (eCS), is a complex system, comprising the main endogenous ligands anandamide and 2-arachidonoyl glycerol, the cannabinoid receptors CB1 and CB2 and the biosynthetic and degrading enzymes. ...
New pyridone-based derivatives as cannabinoid receptor type 2 agonists
(MDPI, 2021)
The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R). In this work ...
New Pyridone-Based Derivatives as Cannabinoid Receptor Type 2 Agonists
(MDPI, 2021)
The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R). In this work ...
Opposing Roles for Cannabinoid Receptor Type-1 (CB1) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats
(NATURE PUBLISHING GROUPLONDON, 2013-08-02)
The midbrain dorsal periaqueductal gray (dPAG) has an important role in orchestrating anxiety-and panic-related responses. Given the cellular and behavioral evidence suggesting opposite functions for cannabinoid type 1 ...
Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia
(Elsevier B.V., 2012-04-23)
Rats exposed to an elevated plus maze (EPM) with four open arms display antinociception while on the maze and hyperalgesia immediately upon removal. Little is known about the neural mechanisms underlying EPM-induced ...
Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia
(Elsevier B.V., 2012-04-23)
Rats exposed to an elevated plus maze (EPM) with four open arms display antinociception while on the maze and hyperalgesia immediately upon removal. Little is known about the neural mechanisms underlying EPM-induced ...