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Comparison of Strategies for the Production of FMDV Empty Capsids Using the Baculovirus Vector System
(Springer, 2014-06)
Recombinant FMDV empty capsids have been produced in insect cells and larvae using the baculovirus expression system, although protein yield and efficiency of capsid assembly have been highly variable. In this work, two ...
Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids
(Taylor & Francis, 2019-01)
Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which causes severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...
Transient Gene Expression in Serum-Free Suspension-Growing Mammalian Cells for the Production of Foot-and-Mouth Disease Virus Empty Capsids
(Public Library of Science, 2013-08)
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. It produces severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...
X-ray structure of Triatoma virus empty capsid: Insights into the mechanism of uncoating and RNA release in dicistroviruses
(Society for General Microbiology, 2016-10)
In viruses, uncoating and RNA release are two key steps of successfully infecting a target cell. During these steps, the capsid must undergo the necessary conformational changes to allow RNA egress. Despite their importance, ...
Cryo-electron microscopy reconstructions of triatoma virus particles: a clue to unravel genome delivery and capsid disassembly
(Society For General Microbiology, 2013-03)
Triatoma virus (TrV), a positive-sense ssRNA virus with a small spherical non-enveloped capsid of ~300 Å in diameter ( Muscio et al., 1988 ; Czibener et al., 2000 ), belongs to the genus Cripavirus (type species: cricket ...
Comparison of strategies for the production of FMDV empty capsids using the Baculovirus Vector System
(Springer, 2014-11)
Recombinant FMDV empty capsids have been produced in insect cells and larvae using the baculovirus expression system, although protein yield and efficiency of capsid assembly have been highly variable. In this work, two ...
Capsid protein identification and analysis of mature Triatoma virus (TrV) virions and naturally occurring empty particles
(Academic Press Inc Elsevier Science, 2011-01)
Triatoma virus (TrV) is a non-enveloped +ssRNA virus belonging to the insect virus family Dicistroviridae. Mass spectrometry (MS) and gel electrophoresis were used to detect the previously elusive capsid protein VP4. Its ...
Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids
(Taylor & Francis, 2019-05)
Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which causes severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...
Transient gene expression in serum-free suspension-growing mammalian cells for the production of foot-and-mouth disease virus empty capsids
(PLOS, 2013-08-20)
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. It produces severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...
Comparison of transient and stable expression of foot-and-mouth disease virus capsid proteins in mammalian cells
(Scientific Research Publishing, 2013-09)
Foot-and-mouth disease is a highly contagious disease that produces severe economic losses in the livestock industry. This disease is being controlled by the use of an inactivated vaccine. However, the use of recombinant ...