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Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides
(Academic Press Inc., 2017)
© 2017 Elsevier Inc. Amyloids are polypeptide aggregates involved in many pathologies including Alzheimer's disease. Amyloid assembly is a complex process affected by different interactions including hydrogen bonding, van ...
Electrostatic interactions at the microscale modulate dynamics and distribution of lipids in bilayers
(Royal Society of Chemistry, 2017-02)
For decades, it has been assumed that electrostatic long-range (micron distances) repulsions in lipid bilayers are negligible due to screening from the aqueous milieu. This concept, mostly derived from theoretical calculations, ...
Size-tunable LDH-protein hybrids towards the optimization of drug nanocarriers
(Royal Society of Chemistry, 2015-02-18)
Layered double hydroxides (LDHs) are extensively investigated as drug nanocarriers due to their anion exchange properties and potential capacity to achieve enhanced cellular trafficking and targeted delivery. In this work, ...
Dielectric exchange: The key repulsive or attractive transient forces between atomic force microscope tips and charged surfaces
(Amer Inst PhysicsWoodburyEUA, 1999)
Solubilization of Alkylpyridinium Ions in Cationic Micelles: Effect of the Electrostatic Repulsion
(1993)
Binding constants of n-alkylpyridinium, CnPd+ (n = 10, 11, 12, 13, 14, and 16), to CTAX micelles, where X = Br− and Cl−, and to CTAOTOS were determined by ultrafiltration and a steady-state fluorescence method. These ...
Electrostatic Unfolding and Interactions of Albumin Driven by pH Changes: A Molecular Dynamics Study
(American Chemical Society, 2014-01)
A better understanding of protein aggregation is bound to translate into<br />critical advances in several areas, including the treatment of misfolded protein disorders and the development of self-assembling biomaterials ...
Electrostatic and Hydrophobic Interactions Involved in CNT Biofunctionalization with Short ss-DNA
(AMER CHEMICAL SOC, 2010)
This work is aimed at studying the adsorption mechanism of short chain 20-mer pyrimidinic homoss-DNA (oligodeoxyribonucleotide, ODN: polyC(20) and polyT(20)) onto CNT by reflectometry. To analyze the experimental data, the ...
Counterion condensation on polyelectrolyte chains adsorbed on charged surfaces
(Elsevier Science, 2015-09-20)
We developed a Monte Carlo systematic study into the effect of counterion condensation on the polyelectrolyte adsorption process on charged surfaces. Polyelectrolyte is modeled as a full-flexible chain whose size is ...
Effect of ionic strength solution on the stability of chitosan-DNA nanoparticles
(2013-07-01)
Chitosan-DNA nanoparticles employed in gene therapy protocols consist of a neutralised, stoichiometric core and a shell of the excess of chitosan which stabilises the particles against further coagulation. At low ionic ...