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Electrostatic Interactions Are Not Sufficient to Account for Chitosan Bioactivity
(AMER CHEMICAL SOC, 2010)
Recent studies involving chitosan interacting with phospholipid monolayers that mimic cell membranes have brought molecular-level evidence for some of the physiological actions of chitosan, as in removing a protein from ...
Understanding the role of electrostatic interactions on the association of 5-fluorouracil to chitosan-TPP nanoparticles
(2022-05-05)
Judicious design strategies should be considered powerful tools to better control the properties of chitosan (CS) and tripolyphosphate (TPP) particles. This study focused on understanding the role of the charge properties ...
The interfacial properties of the peptide Polybia-MP1 and its interaction with DPPC are modulated by lateral electrostatic attractions
(Elsevier Science, 2016-02)
Polybia-MP1 (IDWKKLLDAAKQIL-NH2), extracted from the Brazilian wasp Polybia paulista, exhibits a broad-spectrum bactericidal activity without being hemolytic and cytotoxic. In the present study, we analyzed the surface ...
Electrostatic Unfolding and Interactions of Albumin Driven by pH Changes: A Molecular Dynamics Study
(American Chemical Society, 2014-01)
A better understanding of protein aggregation is bound to translate into<br />critical advances in several areas, including the treatment of misfolded protein disorders and the development of self-assembling biomaterials ...
Biological activity of antibacterial peptides matches synergism between electrostatic and non electrostatic forces
(Elsevier Science, 2014-07)
Substitution of Ala 108 and Ala 111 in the 107–115 human lysozyme (hLz) fragment results in a 20- fold increased anti-staphylococcal activity while its hemolytic activity becomes significant (30%) at very high concentrations. ...
Integral Representation of Electrostatic Interactions inside a Lipid Membrane
(2020-09-01)
Interactions between charges and dipoles inside a lipid membrane are partially screened. The screening arises both from the polarization of water and from the structure of the electric double layer formed by the salt ions ...
O/W emulsions stabilized by interactions between proteins and polysaccharides
(2018-01-01)
Amphiphilic structures can be produced from interactions between proteins and polysaccharides, resulting in supramolecular microstructures very suitable to replace synthetic emulsifiers. These association colloids may be ...