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Identification and pharmacological induction of autophagy in the larval stages of Echinococcus granulosus: an active catabolic process in calcareous corpuscles
(Elsevier, 2014-06)
Autophagy is a fundamental catabolic pathway conserved from yeast to mammals, but which remains unknown in parasite cestodes. In this work, the pharmacological induction of autophagy was cellularly and molecularly analysed ...
Metformin promotes autophagy in Echinococcus granulosus larval stage
(Elsevier Science, 2018-09)
Cystic echinococcosis is a neglected parasitic disease caused by the larval stage of Echinococcus granulosus for which an effective treatment is not yet available. Since autophagy constitutes a homeostatic mechanism during ...
Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in echinococcus granulosus larval stage
(Public Library of Science, 2017-08)
Cystic echinococcosis (CE) is a worldwide distributed helminthic zoonosis caused by Echinococcus granulosus. Benzimidazole derivatives are currently the only drugs for chemotherapeutic treatment of CE. However, their low ...
In vitro anti-echinococcal effects of octreotide on the larval stage of Echinococcus granulosus.
(Elsevier Science, 2020-03)
Cystic echinococcosis (CE) is a worldwide zoonosis caused by the Echinococcus granulosus larval stage. The currently available therapy for this disease is based on benzimidazoles, which are rarely curative and cause several ...
Identificación y validación funcional de nuevos genes y mutaciones asociadas a la etiología de la insuficiencia ovárica primaria (IOP) : implicación de los genes BMP15, BMPR2, MSH4, ATG7, ATG9A y NOTCH2
(Universidad del RosarioDoctorado en Ciencias BiomédicasFacultad de Ciencias Naturales y Matemáticas, 2018)
Primary ovarian insufficiency (POI) is a frequent pathology affecting 1% - 3% of women from the general population under 40 years old. There are not specific data related Colombian population, however, this could be an ...
MON-235 Bone Morphogenic Protein Receptor Variants: A New Cause of Primary Ovarian Insufficiency
Primary ovarian insufficiency (POI) is a major cause of infertility. This disease is characterized by amenorrhea with an increase in gonadotropin levels and affects 1% of women before the age of 40. POI may be the result ...
Procedencia de las areniscas del eoceno temprano (ypresiano) del pozo anh-piedras blancas-1x (cinturón plegado san jacinto) y su relación con la paleogeografía de la margen caribe colombiana
(Facultad de Ciencias Exactas y NaturalesManizalesMaestría en Ciencias de la Tierra, 2021)