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Efficacy and safety of immunological adjuvants. Where is the cut-off?
(2018-09-01)
Research over the past several decades has provided insight into the mode of action of adjuvants. However, the main focus of attention has been the efficacy in the induction of protective immunogenicity, while less effort ...
Evaluation of clinical safety and anthelmintic efficacy of aurixazole administed orally at 24 mg/kg in cattle
(Elsevier B.V., 2014-06-01)
The current study evaluated, in vivo, the clinical safety and the anthelmintic efficacy of 24% aurixazole (24 mg/kg), administered orally, in bovines. Two experiments were conducted: the first one evaluating the clinical ...
Efficacy and safety of recently approved drugs for sickle cell disease: A review of clinical trials
Sickle cell disease is prevalent in several parts of the world. Most of the hospitalizations in these
patients are related to pain crisis episodes. Moreover, the levels of hemoglobin are lower in
sickle cell disease ...
Efficacy and safety of glucose, glucose and polidocanol combination, liquid polidocanol and polidocanol foam in the treatment of reticular veins: A randomized study in rabbits
(2021-05-01)
Objective: To compare the efficacy and safety of sclerosing agents injected in dorsal veins of rabbit ears. Methods: Sixty ears of 30 rabbits were randomly allocated in: 1% liquid polidocanol, 1% polidocanol foam, 0.2% ...
Methodology, efficacy and safety of fecal microbiota transplant in treating inflammatory bowel disease
Fecal microbiota transplantation (FMT), as an emerging therapy, can be used to treat microbiota related diseases.
Progresses in donor screening, washed microbiota preparation, microbiota delivery routes, clinical ...
Randomized clinical trial to evaluate safety and efficacy of convalescent plasma use among hospitalized patients with COVID-19 (PERUCONPLASMA): a structured summary of a study protocol for a randomized controlled trial
(BioMed Central, 2021)
Objectives: The general objective of this study is to test the hypothesis that administration of convalescent plasma from donors with previous diagnosis of severe COVID-19 pneumonia is safe and associated with a decrease ...
Nanoparticles for cosmetic use and its application
(2019-01-01)
Nanoparticles have been cited as a tool to solve many pharmaceutical problems, also in the cosmetic field. Some advantages in using them are to vectorize or retard the release and action of a cosmetic active substance, to ...
In vitro and in vivo evaluation of efficacy and safety of photoprotective formulations containing antioxidant extracts
(Sociedade Brasileira de Farmacognosia, 2016)
Safety and Efficacy of Darunavir/Ritonavir in Treatment-experienced Pediatric Patients: Week 48 Results of the ARIEL Trial
(Lippincott, Williams & Wilkins, 2016)