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Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
(Associação Brasileira de Divulgação Científica, 2014-08-01)
Regulatory T (TREG) cells play an important role in maintaining immune tolerance and avoiding autoimmunity. We analyzed the expression of membrane molecules in TREG and effector T cells in systemic lupus erythematosus ...
Expression Profiling during Arabidopsis/Downy Mildew Interaction Reveals a Highly-Expressed Effector That Attenuates Responses to Salicylic Acid
(Public Library of Science, 2014-10)
Plants have evolved strong innate immunity mechanisms, but successful pathogens evade or suppress plant immunity via effectors delivered into the plant cell. Hyaloperonospora arabidopsidis (Hpa) causes downy mildew on ...
Structural analysis of effector functions related motifs, complement activation and hemagglutinating activities in Lama glama heavy chain antibodies
(Elsevier Science, 2012-01)
Heavy chain antibodies (HCAbs), devoid of the light chains and the CH 1 domain, are present in the serum of camelids. IgG 2 and IgG 3 are HCAbs; whereas IgG 1 has the conventional structure. In order to study the immunological ...
HLA-DR marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients
(American Association of Immunologists, 2021)
Upon Ag encounter, T cells can rapidly divide and form an effector population, which plays an important role in fighting acute infections. In humans, little is known about the molecular markers that distinguish such effector ...
Understanding and exploiting late blight resistance in the age of effectors
(Annual Reviews, 2011-09)
Potato (Solanum tuberosum) is the world's third-largest food crop. It severely suffers from late blight, a devastating disease caused by Phytophthora infestans. This oomycete pathogen secretes host-translocated RXLR effectors ...
PthA4AT, a 7.5-repeats transcription activator-like (TAL) effector from Xanthomonas citri ssp. citri, triggers citrus canker resistance
(Wiley Blackwell Publishing, Inc, 2019-06)
Transcription activator-like effectors (TALEs) are important effectors of Xanthomonas spp. that manipulate the transcriptome of the host plant, conferring susceptibility or resistance to bacterial infection. Xanthomonas ...
PthA4AT, a 7.5-repeats transcription activator-like (TAL) effector from Xanthomonas citri ssp. citri, triggers citrus canker resistance
(Wiley Blackwell Publishing, Inc, 2019-10)
Transcription activator-like effectors (TALEs) are important effectors of Xanthomonas spp. that manipulate the transcriptome of the host plant, conferring susceptibility or resistance to bacterial infection. Xanthomonas ...
Intracellular and extracellular effector activity of mouse neutrophils in response to cutaneous and visceral Leishmania parasites
(Elsevier B.V., 2019-01-01)
Neutrophils are short-lived phagocytic cells equipped with several receptors for pathogen recognition and phagocytosis and have intracellular and extracellular effector mechanisms that can inactivate pathogens. Leishmaniases ...
A Downy Mildew Effector Attenuates Salicylic Acid–Triggered Immunity in Arabidopsis by Interacting with the Host Mediator Complex
(Public Library Science, 2013-12-10)
Plants are continually exposed to pathogen attack but usually remain healthy becausethey can activate defences upon perception of microbes. However, pathogens haveevolved to overcome plant immunity by delivering effectors ...
Identification of Type VI Secretion Systems Effector Proteins That Contribute to Interbacterial Competition in Salmonella Dublin
(FRONTIERS MEDIA SA, 2022)
The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or ...