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Efficacy of albendazole in combination with thymol against Echinococcus multilocularis protoscoleces and metacestodes
(Elsevier Science, 2014-08)
The larval (metacestode) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a mainly hepatic disease characterized by continuous asexual proliferation of metacestodes by exogenous budding, ...
In vivo activity of albendazole in combination with thymol against Echinococcus multilocularis
(Elsevier Science, 2015-09)
Human alveolar echinococcosis (AE) is caused by the fox tapeworm Echinococcus multilocularis and is usually lethal if left untreated. The current strategy for treating human AE is surgical resection of the parasite mass ...
Fatty acid-binding proteins in Echinococcus spp.: the family has grown
(Springer, 2020-03)
Fatty acid-binding proteins (FABPs) are small intracellular proteins that reversibly bind fatty acids and other hydrophobic ligands. In cestodes, due to their inability to synthesise fatty acids de novo, FABPs have been ...
The nervous and prenervous roles of serotonin in Echinococcus spp.
(Elsevier, 2013-03)
Serotonin (5-hydroxytryptamine, 5-HT) is an important neuroactive and morphogenetic molecule in several metazoan phyla, including flatworms. Serotoninergic nervous system studies are incomplete and 5-HT function/s are ...
MicroRNA discovery in the human parasite Echinococcus multilocularis from genome-wide data
(Academic Press Inc Elsevier Science, 2016-04)
The cestode parasite Echinococcus multilocularis is the aetiological agent of alveolar echinococcosis, responsible for considerable human morbidity and mortality. This disease is a worldwide zoonosis of major public health ...
Expression profiling of Echinococcus multilocularis miRNAs throughout metacestode development in vitro
(PLOS, 2021)
The neglected zoonotic disease alveolar echinococcosis (AE) is caused by the metacestode stage of the tapeworm parasite Echinococcus multilocularis. MicroRNAs (miRNAs) are small non-coding RNAs with a major role in regulating ...