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E-cadherin and beta-catenin Loss of Expression Related to Bone Metastasis in Prostate Cancer
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Objectives: E-cadherin and beta-catenin are adhesion molecules responsible for the maintenance of normal epithelial cell phenotype. A disturbance in epithelial cell adhesion, which leads to a more invasive and metastatic ...
E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer
(2019-11-29)
E-cadherin is a transmembrane glycoprotein responsible for cell-to-cell adhesion, and its loss has been associated with metastasis development. Although E-cadherin downregulation was previously reported in canine prostate ...
Role of adhesion molecules and proliferation hyperplasic, pre neoplastic and neoplastic lesions in canine prostate
(2013-05-01)
E-cadherin and beta-catenin are component of adherens junctions in epithelial cells. Loss of these proteins have been associated with progression of prostatic diseases. We performed immunohistochemistry for E-cadherin, ...
E-cadherin abnormalities resulting from CPG methylation promoter in metastatic and nonmetastatic oral cancer
(JOHN WILEY & SONS INC, 2008)
Background. This study aims to compare the alterations in the methylation profiles of E-cadherin in oral cancer, especially in tumors with lowest metatastic potential. Methods. Nine oral verrucous carcinomas (VCs), 20 oral ...
E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors
(ELSEVIER SCI LTDOXFORD, 2012)
Mast cell tumors (MCTs) are the most frequent round cell tumors in dogs and comprise approximately 21% of all canine cutaneous tumors. MCTs are highly invasive and metastatic corresponding to the histological grade. ...
E-cadherin expression pattern during zebrafish embryonic epidermis development [version 3; referees: 3 approved]
(F1000 Research Ltd, 2018-12)
Background: E-cadherin is the major adhesion receptor in epithelial adherens junctions (AJs). On established epidermis, E-cadherin performs fine-tuned cell-cell contact remodeling to maintain tissue integrity, which is ...
Immunohistochemical evaluation of Ki-67 and PCNA in canine mammary neoplasias: Correlation with prognostic factors and clinical outcome
(Revista Pesquisa Veterinaria Brasileira, 2008-04-01)
E-cadherin is a cell-cell adhesion molecule and low e-cadherin expression is related to invasiveness and may indicate a bad prognosis in mammary neoplasms. The expression of cell proliferation markers PCNA and especially ...
Immunohistochemical evaluation of Ki-67 and PCNA in canine mammary neoplasias: Correlation with prognostic factors and clinical outcome
(Revista Pesquisa Veterinaria Brasileira, 2008-04-01)
E-cadherin is a cell-cell adhesion molecule and low e-cadherin expression is related to invasiveness and may indicate a bad prognosis in mammary neoplasms. The expression of cell proliferation markers PCNA and especially ...