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Epigenetic alterations related to early-life stressful events
(Cambridge University Press, 2012)
Objective Early stress events severely impact brain and behaviour. From a neurobiological point of view early stress influences neuroanatomical structures and is associated with a dysregulation of the hypothalamic-pituit ...
Long-term effects of early life stress exposure: role of epigenetic mechanisms
(Elsevier, 2016-07)
Stress is an adaptive response to demands of the environment and thus essential for survival. Exposure to stress during the first years of life has been shown to have profound effects on the growth and development of an ...
How does early maternal separation and chronic stress in adult rats affect the immunoreactivity of serotonergic neurons within the dorsal raphe nucleus?
(Taylor & Francis Ltd, 2018-01)
Vulnerability to emotional disorders like depression derives from interactions between early and late environments, including stressful conditions. The serotonin (5HT) system is strongly affected by stress and chronic ...
Behavioral and neuroendocrine effects of the exposure to chronic restraint or variable stress in early adolescent rats
(Pergamon-Elsevier B.V. Ltd, 2012-02-01)
Stress events during adolescence may contribute to the expression or exacerbation of physical and behavioral disorders. However, little attention has been given to the physiological and behavioral changes promoted by stress ...
Behavioral and neuroendocrine effects of the exposure to chronic restraint or variable stress in early adolescent rats
(Pergamon-Elsevier B.V. Ltd, 2012-02-01)
Stress events during adolescence may contribute to the expression or exacerbation of physical and behavioral disorders. However, little attention has been given to the physiological and behavioral changes promoted by stress ...
Early responsive to DEHYDRATION 15, a new transcription factor that integrates stress signaling pathways
(Plant Signaling & Behavior, 2017)
Effects of early and late adverse experiences on intake behavior of rats subjected to stress during adulthood
(Interciencia, 2016)
The aim of this study was to ascertain the effect on intake behavior, in adult rats subjected to intermittent chronic stress, through the alteration of the early rat-breeding linkage and altering the late social linkage ...
Effect of maternal separation and chronic stress on hippocampal-dependent memory in young adult rats: evidence for the match-mismatch hypothesis
(Taylor & Francis Ltd, 2014-09)
Adverse experiences early in life may sensitize the hippocampus to subsequent stressors throughout the individual's life. We analyzed in male rats, whether, the interaction between early maternal separation and chronic ...
Microglial memory of early life stress and inflammation: Susceptibility to neurodegeneration in adulthood
(Pergamon-Elsevier Science Ltd, 2019-11)
We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding ...
A novel transcription factor, ERD15 (Early Responsive to Dehydration 15), connects Endoplasmic Reticulum stress with an osmotic stress-induced cell death signal
(The Journal of Biological Chemistry, 2017)